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Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants.
Majumdar S, Subrath J, Le Rouzic V, Polikar L, Burgman M, Nagakura K, Ocampo J, Haselton N, Pasternak AR, Grinnell S, Pan YX, Pasternak GW. Majumdar S, et al. Among authors: le rouzic v. J Med Chem. 2012 Jul 26;55(14):6352-62. doi: 10.1021/jm300305c. Epub 2012 Jul 16. J Med Chem. 2012. PMID: 22734622 Free PMC article.
Novel 6β-acylaminomorphinans with analgesic activity.
Váradi A, Hosztafi S, Le Rouzic V, Tóth G, Urai Á, Noszál B, Pasternak GW, Grinnell SG, Majumdar S. Váradi A, et al. Among authors: le rouzic v. Eur J Med Chem. 2013 Nov;69:786-9. doi: 10.1016/j.ejmech.2013.09.031. Epub 2013 Sep 22. Eur J Med Chem. 2013. PMID: 24103580 Free PMC article.
Synthesis of Carfentanil Amide Opioids Using the Ugi Multicomponent Reaction.
Váradi A, Palmer TC, Haselton N, Afonin D, Subrath JJ, Le Rouzic V, Hunkele A, Pasternak GW, Marrone GF, Borics A, Majumdar S. Váradi A, et al. Among authors: le rouzic v. ACS Chem Neurosci. 2015 Sep 16;6(9):1570-7. doi: 10.1021/acschemneuro.5b00137. Epub 2015 Jul 21. ACS Chem Neurosci. 2015. PMID: 26148793 Free PMC article.
Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.
Váradi A, Marrone GF, Palmer TC, Narayan A, Szabó MR, Le Rouzic V, Grinnell SG, Subrath JJ, Warner E, Kalra S, Hunkele A, Pagirsky J, Eans SO, Medina JM, Xu J, Pan YX, Borics A, Pasternak GW, McLaughlin JP, Majumdar S. Váradi A, et al. Among authors: le rouzic v. J Med Chem. 2016 Sep 22;59(18):8381-97. doi: 10.1021/acs.jmedchem.6b00748. Epub 2016 Sep 2. J Med Chem. 2016. PMID: 27556704 Free PMC article.
24 results