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Evaluation of Combination Strategies for the A2AR Inhibitor AZD4635 Across Tumor Microenvironment Conditions via a Systems Pharmacology Model.
Voronova V, Peskov K, Kosinsky Y, Helmlinger G, Chu L, Borodovsky A, Woessner R, Sachsenmeier K, Shao W, Kumar R, Pouliot G, Merchant M, Kimko H, Mugundu G. Voronova V, et al. Among authors: helmlinger g. Front Immunol. 2021 Mar 2;12:617316. doi: 10.3389/fimmu.2021.617316. eCollection 2021. Front Immunol. 2021. PMID: 33737925 Free PMC article.
Quantitative Systems Pharmacology: An Exemplar Model-Building Workflow With Applications in Cardiovascular, Metabolic, and Oncology Drug Development.
Helmlinger G, Sokolov V, Peskov K, Hallow KM, Kosinsky Y, Voronova V, Chu L, Yakovleva T, Azarov I, Kaschek D, Dolgun A, Schmidt H, Boulton DW, Penland RC. Helmlinger G, et al. CPT Pharmacometrics Syst Pharmacol. 2019 Jun;8(6):380-395. doi: 10.1002/psp4.12426. Epub 2019 Jun 11. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31087533 Free PMC article. Review.
Longitudinal Tumor Size and Neutrophil-to-Lymphocyte Ratio Are Prognostic Biomarkers for Overall Survival in Patients With Advanced Non-Small Cell Lung Cancer Treated With Durvalumab.
Gavrilov S, Zhudenkov K, Helmlinger G, Dunyak J, Peskov K, Aksenov S. Gavrilov S, et al. Among authors: helmlinger g. CPT Pharmacometrics Syst Pharmacol. 2021 Jan;10(1):67-74. doi: 10.1002/psp4.12578. Epub 2020 Dec 21. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33319498 Free PMC article.
A workflow for the joint modeling of longitudinal and event data in the development of therapeutics: Tools, statistical methods, and diagnostics.
Zhudenkov K, Gavrilov S, Sofronova A, Stepanov O, Kudryashova N, Helmlinger G, Peskov K. Zhudenkov K, et al. Among authors: helmlinger g. CPT Pharmacometrics Syst Pharmacol. 2022 Apr;11(4):425-437. doi: 10.1002/psp4.12763. Epub 2022 Feb 21. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35064957 Free PMC article.
51 results