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4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects.
Zimmermann A, Kainz K, Hofer SJ, Bauer MA, Schroeder S, Dengjel J, Pietrocola F, Kepp O, Ruckenstuhl C, Eisenberg T, Sigrist SJ, Madeo F, Carmona-Gutierrez D, Kroemer G. Zimmermann A, et al. Among authors: sigrist sj. Autophagy. 2019 Sep;15(9):1662-1664. doi: 10.1080/15548627.2019.1632623. Epub 2019 Jun 28. Autophagy. 2019. PMID: 31248332 Free PMC article.
Endonuclease G regulates budding yeast life and death.
Büttner S, Eisenberg T, Carmona-Gutierrez D, Ruli D, Knauer H, Ruckenstuhl C, Sigrist C, Wissing S, Kollroser M, Fröhlich KU, Sigrist S, Madeo F. Büttner S, et al. Mol Cell. 2007 Jan 26;25(2):233-46. doi: 10.1016/j.molcel.2006.12.021. Mol Cell. 2007. PMID: 17244531 Free article.
The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models.
Büttner S, Faes L, Reichelt WN, Broeskamp F, Habernig L, Benke S, Kourtis N, Ruli D, Carmona-Gutierrez D, Eisenberg T, D'hooge P, Ghillebert R, Franssens V, Harger A, Pieber TR, Freudenberger P, Kroemer G, Sigrist SJ, Winderickx J, Callewaert G, Tavernarakis N, Madeo F. Büttner S, et al. Among authors: sigrist sj. Cell Death Differ. 2013 Mar;20(3):465-77. doi: 10.1038/cdd.2012.142. Epub 2012 Nov 16. Cell Death Differ. 2013. PMID: 23154387 Free PMC article.
Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner.
Gupta VK, Scheunemann L, Eisenberg T, Mertel S, Bhukel A, Koemans TS, Kramer JM, Liu KS, Schroeder S, Stunnenberg HG, Sinner F, Magnes C, Pieber TR, Dipt S, Fiala A, Schenck A, Schwaerzel M, Madeo F, Sigrist SJ. Gupta VK, et al. Among authors: sigrist sj. Nat Neurosci. 2013 Oct;16(10):1453-60. doi: 10.1038/nn.3512. Epub 2013 Sep 1. Nat Neurosci. 2013. PMID: 23995066
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease.
Büttner S, Habernig L, Broeskamp F, Ruli D, Vögtle FN, Vlachos M, Macchi F, Küttner V, Carmona-Gutierrez D, Eisenberg T, Ring J, Markaki M, Taskin AA, Benke S, Ruckenstuhl C, Braun R, Van den Haute C, Bammens T, van der Perren A, Fröhlich KU, Winderickx J, Kroemer G, Baekelandt V, Tavernarakis N, Kovacs GG, Dengjel J, Meisinger C, Sigrist SJ, Madeo F. Büttner S, et al. Among authors: sigrist sj. EMBO J. 2013 Nov 27;32(23):3041-54. doi: 10.1038/emboj.2013.228. Epub 2013 Oct 15. EMBO J. 2013. PMID: 24129513 Free PMC article.
Spermidine-triggered autophagy ameliorates memory during aging.
Sigrist SJ, Carmona-Gutierrez D, Gupta VK, Bhukel A, Mertel S, Eisenberg T, Madeo F. Sigrist SJ, et al. Autophagy. 2014 Jan;10(1):178-9. doi: 10.4161/auto.26918. Epub 2013 Nov 15. Autophagy. 2014. PMID: 24262970 Free PMC article.
Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.
Eisenberg T, Schroeder S, Andryushkova A, Pendl T, Küttner V, Bhukel A, Mariño G, Pietrocola F, Harger A, Zimmermann A, Moustafa T, Sprenger A, Jany E, Büttner S, Carmona-Gutierrez D, Ruckenstuhl C, Ring J, Reichelt W, Schimmel K, Leeb T, Moser C, Schatz S, Kamolz LP, Magnes C, Sinner F, Sedej S, Fröhlich KU, Juhasz G, Pieber TR, Dengjel J, Sigrist SJ, Kroemer G, Madeo F. Eisenberg T, et al. Among authors: sigrist sj. Cell Metab. 2014 Mar 4;19(3):431-44. doi: 10.1016/j.cmet.2014.02.010. Cell Metab. 2014. PMID: 24606900 Free PMC article.
A histone point mutation that switches on autophagy.
Eisenberg T, Schroeder S, Büttner S, Carmona-Gutierrez D, Pendl T, Andryushkova A, Mariño G, Pietrocola F, Harger A, Zimmermann A, Magnes C, Sinner F, Sedej S, Pieber TR, Dengjel J, Sigrist S, Kroemer G, Madeo F. Eisenberg T, et al. Autophagy. 2014 Jun;10(6):1143-5. doi: 10.4161/auto.28767. Autophagy. 2014. PMID: 24879160 Free PMC article.
175 results