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Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution.
Fürstner C, Ackerstaff J, Meier H, Straub A, Mittendorf J, Schamberger J, Schäfer M, Börngen K, Jörißen H, Zubov D, Zimmermann K, Tersteegen A, Geiss V, Hartmann E, Albrecht-Küpper B, D'Orléans-Juste P, Lapointe C, Vincent L, Heitmeier S, Tinel H. Fürstner C, et al. Among authors: lapointe c. J Med Chem. 2024 Nov 14. doi: 10.1021/acs.jmedchem.4c01819. Online ahead of print. J Med Chem. 2024. PMID: 39541507
eIF1 and eIF5 dynamically control translation start site fidelity.
Grosely R, Alvarado C, Ivanov IP, Nicholson OB, Puglisi JD, Dever TE, Lapointe CP. Grosely R, et al. Among authors: lapointe cp. bioRxiv [Preprint]. 2024 Jul 13:2024.07.10.602410. doi: 10.1101/2024.07.10.602410. bioRxiv. 2024. PMID: 39026837 Free PMC article. Preprint.
102 results