Chen Z - Search Results

1

Cost-effectiveness Analysis of Pembrolizumab Plus Axitinib Versus Sunitinib in First-line Advanced Renal Cell Carcinoma in China.

Chen J, Hu G, Chen Z, Wan X, Tan C, Zeng X, Cheng Z. Chen J, et al. Among authors: chen z. Clin Drug Investig. 2019 Oct;39(10):931-938. doi: 10.1007/s40261-019-00820-6. Clin Drug Investig. 2019. PMID: 31250401

2

An emerging strategy for targeted therapy of pulmonary arterial hypertension: Vasodilation plus vascular remodeling inhibition.

Hu L, Zhao C, Chen Z, Hu G, Li X, Li Q. Hu L, et al. Among authors: chen z. Drug Discov Today. 2022 May;27(5):1457-1463. doi: 10.1016/j.drudis.2022.01.011. Epub 2022 Jan 29. Drug Discov Today. 2022. PMID: 35104622 Review.

3

9za plays cytotoxic and proapoptotic roles and induces cytoprotective autophagy through the PDK1/Akt/mTOR axis in non-small-cell lung cancer.

Liu R, Chen Z, Yi X, Huang F, Hu G, Liu D, Li X, Zhou H, Liu Z. Liu R, et al. Among authors: chen z. J Cell Physiol. 2019 Nov;234(11):20728-20741. doi: 10.1002/jcp.28679. Epub 2019 Apr 19. J Cell Physiol. 2019. Retraction in: J Cell Physiol. 2022 May;237(5):2600. doi: 10.1002/jcp.30741 PMID: 31004362 Retracted.

4

Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents.

Chang Q, Long J, Hu L, Chen Z, Li Q, Hu G. Chang Q, et al. Among authors: chen z. Bioorg Med Chem. 2020 May 1;28(9):115404. doi: 10.1016/j.bmc.2020.115404. Epub 2020 Mar 3. Bioorg Med Chem. 2020. PMID: 32216987

5

Design, synthesis, and biological evaluation of 1,2,4-oxadiazole-containing pyrazolo[3,4-b]pyridinones as a new series of AMPKɑ1β1γ1 activators.

Xiao Z, Peng Y, Zheng B, Chang Q, Guo Y, Chen Z, Li Q, Hu G. Xiao Z, et al. Among authors: chen z. Arch Pharm (Weinheim). 2021 Jul;354(7):e2000458. doi: 10.1002/ardp.202000458. Epub 2021 Mar 8. Arch Pharm (Weinheim). 2021. PMID: 33683726

6

Binding pocket-based design, synthesis and biological evaluation of novel selective BRD4-BD1 inhibitors.

Ma J, Chen H, Yang J, Yu Z, Huang P, Yang H, Zheng B, Liu R, Li Q, Hu G, Chen Z. Ma J, et al. Among authors: chen z, chen h. Bioorg Med Chem. 2019 May 1;27(9):1871-1881. doi: 10.1016/j.bmc.2019.03.037. Epub 2019 Mar 22. Bioorg Med Chem. 2019. PMID: 30926312

7

Soluble Guanylate Cyclase Stimulators and Activators: Where are We and Where to Go?

Xiao S, Li Q, Hu L, Yu Z, Yang J, Chang Q, Chen Z, Hu G. Xiao S, et al. Among authors: chen z. Mini Rev Med Chem. 2019;19(18):1544-1557. doi: 10.2174/1389557519666190730110600. Mini Rev Med Chem. 2019. PMID: 31362687 Review.

8

Synthesis and structure-activity relationships of pyrazolo-[3,4-b]pyridine derivatives as adenosine 5'-monophosphate-activated protein kinase activators.

Zheng B, Peng Y, Wu W, Ma J, Zhang Y, Guo Y, Sun S, Chen Z, Li Q, Hu G. Zheng B, et al. Among authors: chen z. Arch Pharm (Weinheim). 2019 Aug;352(8):e1900066. doi: 10.1002/ardp.201900066. Arch Pharm (Weinheim). 2019. PMID: 31373047

9

Novel pyrazolo[3,4-b]pyridine derivatives: Synthesis, structure-activity relationship studies, and regulation of the AMPK/70S6K pathway.

Guo Y, Jiang X, Chang Q, Xiao Z, Chen Z, Jiang D, Hu G, Li Q. Guo Y, et al. Among authors: chen z. Arch Pharm (Weinheim). 2022 Jul;355(7):e2100465. doi: 10.1002/ardp.202100465. Epub 2022 Apr 12. Arch Pharm (Weinheim). 2022. PMID: 35415908

10

A novel dual MEK/PDK1 inhibitor 9za retards the cell cycle at G₀/G₁ phase and induces mitochondrial apoptosis in non-small cell lung cancer cells.

Liu R, Yu Z, Chen Z, Liu D, Huang F, Li Q, Hu G, Yi X, Li X, Zhou H, Liu Z. Liu R, et al. Among authors: chen z. PeerJ. 2020 Oct 2;8:e9981. doi: 10.7717/peerj.9981. eCollection 2020. PeerJ. 2020. PMID: 33072436 Free PMC article.

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