Purcell AW - Search Results

1

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses.

Wu T, Guan J, Handel A, Tscharke DC, Sidney J, Sette A, Wakim LM, Sng XYX, Thomas PG, Croft NP, Purcell AW, La Gruta NL. Wu T, et al. Among authors: purcell aw. Nat Commun. 2019 Jun 28;10(1):2846. doi: 10.1038/s41467-019-10661-8. Nat Commun. 2019. PMID: 31253788 Free PMC article.

2

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations.

Turner SJ, Kedzierska K, Komodromou H, La Gruta NL, Dunstone MA, Webb AI, Webby R, Walden H, Xie W, McCluskey J, Purcell AW, Rossjohn J, Doherty PC. Turner SJ, et al. Among authors: purcell aw. Nat Immunol. 2005 Apr;6(4):382-9. doi: 10.1038/ni1175. Epub 2005 Feb 27. Nat Immunol. 2005. PMID: 15735650

3

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.

Tynan FE, Burrows SR, Buckle AM, Clements CS, Borg NA, Miles JJ, Beddoe T, Whisstock JC, Wilce MC, Silins SL, Burrows JM, Kjer-Nielsen L, Kostenko L, Purcell AW, McCluskey J, Rossjohn J. Tynan FE, et al. Among authors: purcell aw. Nat Immunol. 2005 Nov;6(11):1114-22. doi: 10.1038/ni1257. Epub 2005 Sep 25. Nat Immunol. 2005. PMID: 16186824

4

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation.

Tynan FE, Elhassen D, Purcell AW, Burrows JM, Borg NA, Miles JJ, Williamson NA, Green KJ, Tellam J, Kjer-Nielsen L, McCluskey J, Rossjohn J, Burrows SR. Tynan FE, et al. Among authors: purcell aw. J Exp Med. 2005 Nov 7;202(9):1249-60. doi: 10.1084/jem.20050864. J Exp Med. 2005. PMID: 16275762 Free PMC article.

5

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule.

Tynan FE, Reid HH, Kjer-Nielsen L, Miles JJ, Wilce MC, Kostenko L, Borg NA, Williamson NA, Beddoe T, Purcell AW, Burrows SR, McCluskey J, Rossjohn J. Tynan FE, et al. Among authors: purcell aw. Nat Immunol. 2007 Mar;8(3):268-76. doi: 10.1038/ni1432. Epub 2007 Jan 28. Nat Immunol. 2007. PMID: 17259989

6

Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides.

La Gruta NL, Thomas PG, Webb AI, Dunstone MA, Cukalac T, Doherty PC, Purcell AW, Rossjohn J, Turner SJ. La Gruta NL, et al. Among authors: purcell aw. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2034-9. doi: 10.1073/pnas.0711682102. Epub 2008 Jan 31. Proc Natl Acad Sci U S A. 2008. PMID: 18238896 Free PMC article.

7

Enhancing tumor vaccines: catalyzing MHC class II peptide exchange.

Croft NP, Purcell AW. Croft NP, et al. Among authors: purcell aw. Expert Rev Vaccines. 2010 Feb;9(2):129-32. doi: 10.1586/erv.09.159. Expert Rev Vaccines. 2010. PMID: 20109023 Free article. Review.

8

Epitope discovery and their use in peptide based vaccines.

Dudek NL, Perlmutter P, Aguilar MI, Croft NP, Purcell AW. Dudek NL, et al. Among authors: purcell aw. Curr Pharm Des. 2010;16(28):3149-57. doi: 10.2174/138161210793292447. Curr Pharm Des. 2010. PMID: 20687873 Review.

9

Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.

Valkenburg SA, Gras S, Guillonneau C, La Gruta NL, Thomas PG, Purcell AW, Rossjohn J, Doherty PC, Turner SJ, Kedzierska K. Valkenburg SA, et al. Among authors: purcell aw. PLoS Pathog. 2010 Aug 12;6(8):e1001039. doi: 10.1371/journal.ppat.1001039. PLoS Pathog. 2010. PMID: 20711359 Free PMC article.

10

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor.

Pang SS, Berry R, Chen Z, Kjer-Nielsen L, Perugini MA, King GF, Wang C, Chew SH, La Gruta NL, Williams NK, Beddoe T, Tiganis T, Cowieson NP, Godfrey DI, Purcell AW, Wilce MC, McCluskey J, Rossjohn J. Pang SS, et al. Among authors: purcell aw. Nature. 2010 Oct 14;467(7317):844-8. doi: 10.1038/nature09448. Nature. 2010. PMID: 20944746

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