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A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS).
Wu MR, Nissim L, Stupp D, Pery E, Binder-Nissim A, Weisinger K, Enghuus C, Palacios SR, Humphrey M, Zhang Z, Maria Novoa E, Kellis M, Weiss R, Rabkin SD, Tabach Y, Lu TK. Wu MR, et al. Among authors: palacios sr. Nat Commun. 2019 Jun 28;10(1):2880. doi: 10.1038/s41467-019-10912-8. Nat Commun. 2019. PMID: 31253799 Free PMC article.
The sound of silence: Transgene silencing in mammalian cell engineering.
Cabrera A, Edelstein HI, Glykofrydis F, Love KS, Palacios S, Tycko J, Zhang M, Lensch S, Shields CE, Livingston M, Weiss R, Zhao H, Haynes KA, Morsut L, Chen YY, Khalil AS, Wong WW, Collins JJ, Rosser SJ, Polizzi K, Elowitz MB, Fussenegger M, Hilton IB, Leonard JN, Bintu L, Galloway KE, Deans TL. Cabrera A, et al. Cell Syst. 2022 Dec 21;13(12):950-973. doi: 10.1016/j.cels.2022.11.005. Cell Syst. 2022. PMID: 36549273 Free PMC article. Review.
Principles for the design of multicellular engineered living systems.
Aydin O, Passaro AP, Raman R, Spellicy SE, Weinberg RP, Kamm RD, Sample M, Truskey GA, Zartman J, Dar RD, Palacios S, Wang J, Tordoff J, Montserrat N, Bashir R, Saif MTA, Weiss R. Aydin O, et al. APL Bioeng. 2022 Mar 2;6(1):010903. doi: 10.1063/5.0076635. eCollection 2022 Mar. APL Bioeng. 2022. PMID: 35274072 Free PMC article.