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Page 1
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
Roberts JD, Murphy NP, Hamilton RM, Lubbers ER, James CA, Kline CF, Gollob MH, Krahn AD, Sturm AC, Musa H, El-Refaey M, Koenig S, Aneq MÅ, Hoorntje ET, Graw SL, Davies RW, Rafiq MA, Koopmann TT, Aafaqi S, Fatah M, Chiasson DA, Taylor MR, Simmons SL, Han M, van Opbergen CJ, Wold LE, Sinagra G, Mittal K, Tichnell C, Murray B, Codima A, Nazer B, Nguyen DT, Marcus FI, Sobriera N, Lodder EM, van den Berg MP, Spears DA, Robinson JF, Ursell PC, Green AK, Skanes AC, Tang AS, Gardner MJ, Hegele RA, van Veen TA, Wilde AA, Healey JS, Janssen PM, Mestroni L, van Tintelen JP, Calkins H, Judge DP, Hund TJ, Scheinman MM, Mohler PJ. Roberts JD, et al. Among authors: janssen pm. J Clin Invest. 2019 Jul 2;129(8):3171-3184. doi: 10.1172/JCI125538. eCollection 2019 Jul 2. J Clin Invest. 2019. PMID: 31264976 Free PMC article.
Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy.
Acharyya S, Villalta SA, Bakkar N, Bupha-Intr T, Janssen PM, Carathers M, Li ZW, Beg AA, Ghosh S, Sahenk Z, Weinstein M, Gardner KL, Rafael-Fortney JA, Karin M, Tidball JG, Baldwin AS, Guttridge DC. Acharyya S, et al. Among authors: janssen pm. J Clin Invest. 2007 Apr;117(4):889-901. doi: 10.1172/JCI30556. Epub 2007 Mar 22. J Clin Invest. 2007. PMID: 17380205 Free PMC article.
Neuronal Na+ channel blockade suppresses arrhythmogenic diastolic Ca2+ release.
Radwański PB, Brunello L, Veeraraghavan R, Ho HT, Lou Q, Makara MA, Belevych AE, Anghelescu M, Priori SG, Volpe P, Hund TJ, Janssen PM, Mohler PJ, Bridge JH, Poelzing S, Györke S. Radwański PB, et al. Among authors: janssen pm. Cardiovasc Res. 2015 Apr 1;106(1):143-52. doi: 10.1093/cvr/cvu262. Epub 2014 Dec 23. Cardiovasc Res. 2015. PMID: 25538156 Free PMC article.
Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia.
Smith SA, Sturm AC, Curran J, Kline CF, Little SC, Bonilla IM, Long VP, Makara M, Polina I, Hughes LD, Webb TR, Wei Z, Wright P, Voigt N, Bhakta D, Spoonamore KG, Zhang C, Weiss R, Binkley PF, Janssen PM, Kilic A, Higgins RS, Sun M, Ma J, Dobrev D, Zhang M, Carnes CA, Vatta M, Rasband MN, Hund TJ, Mohler PJ. Smith SA, et al. Among authors: janssen pm. Circulation. 2015 Feb 24;131(8):695-708. doi: 10.1161/CIRCULATIONAHA.114.013708. Epub 2015 Jan 28. Circulation. 2015. PMID: 25632041 Free PMC article.
Differential involvement of various sources of reactive oxygen species in thyroxin-induced hemodynamic changes and contractile dysfunction of the heart and diaphragm muscles.
Elnakish MT, Schultz EJ, Gearinger RL, Saad NS, Rastogi N, Ahmed AA, Mohler PJ, Janssen PM. Elnakish MT, et al. Among authors: janssen pm. Free Radic Biol Med. 2015 Jun;83:252-61. doi: 10.1016/j.freeradbiomed.2015.02.035. Epub 2015 Mar 17. Free Radic Biol Med. 2015. PMID: 25795514 Free PMC article.
Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart.
Li N, Csepe TA, Hansen BJ, Dobrzynski H, Higgins RS, Kilic A, Mohler PJ, Janssen PM, Rosen MR, Biesiadecki BJ, Fedorov VV. Li N, et al. Among authors: janssen pm. Circ Arrhythm Electrophysiol. 2015 Oct;8(5):1219-27. doi: 10.1161/CIRCEP.115.003070. Epub 2015 Aug 24. Circ Arrhythm Electrophysiol. 2015. PMID: 26304511 Free PMC article.
SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia.
Musa H, Kline CF, Sturm AC, Murphy N, Adelman S, Wang C, Yan H, Johnson BL, Csepe TA, Kilic A, Higgins RS, Janssen PM, Fedorov VV, Weiss R, Salazar C, Hund TJ, Pitt GS, Mohler PJ. Musa H, et al. Among authors: janssen pm. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12528-33. doi: 10.1073/pnas.1516430112. Epub 2015 Sep 21. Proc Natl Acad Sci U S A. 2015. PMID: 26392562 Free PMC article.
259 results