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Cellular models of alpha-synuclein toxicity and aggregation.
Delenclos M, Burgess JD, Lamprokostopoulou A, Outeiro TF, Vekrellis K, McLean PJ. Delenclos M, et al. Among authors: outeiro tf. J Neurochem. 2019 Sep;150(5):566-576. doi: 10.1111/jnc.14806. Epub 2019 Jul 30. J Neurochem. 2019. PMID: 31265132 Free PMC article. Review.
Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra.
St Martin JL, Klucken J, Outeiro TF, Nguyen P, Keller-McGandy C, Cantuti-Castelvetri I, Grammatopoulos TN, Standaert DG, Hyman BT, McLean PJ. St Martin JL, et al. Among authors: outeiro tf. J Neurochem. 2007 Mar;100(6):1449-57. doi: 10.1111/j.1471-4159.2006.04310.x. Epub 2007 Jan 4. J Neurochem. 2007. PMID: 17241127 Free article.
CHIP targets toxic alpha-Synuclein oligomers for degradation.
Tetzlaff JE, Putcha P, Outeiro TF, Ivanov A, Berezovska O, Hyman BT, McLean PJ. Tetzlaff JE, et al. Among authors: outeiro tf. J Biol Chem. 2008 Jun 27;283(26):17962-8. doi: 10.1074/jbc.M802283200. Epub 2008 Apr 24. J Biol Chem. 2008. PMID: 18436529 Free PMC article.
Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration.
Mollenhauer B, Cullen V, Kahn I, Krastins B, Outeiro TF, Pepivani I, Ng J, Schulz-Schaeffer W, Kretzschmar HA, McLean PJ, Trenkwalder C, Sarracino DA, Vonsattel JP, Locascio JJ, El-Agnaf OM, Schlossmacher MG. Mollenhauer B, et al. Among authors: outeiro tf. Exp Neurol. 2008 Oct;213(2):315-25. doi: 10.1016/j.expneurol.2008.06.004. Epub 2008 Jun 14. Exp Neurol. 2008. PMID: 18625222
Dopamine-induced conformational changes in alpha-synuclein.
Outeiro TF, Klucken J, Bercury K, Tetzlaff J, Putcha P, Oliveira LM, Quintas A, McLean PJ, Hyman BT. Outeiro TF, et al. PLoS One. 2009 Sep 4;4(9):e6906. doi: 10.1371/journal.pone.0006906. PLoS One. 2009. PMID: 19730729 Free PMC article.
354 results