Du X - Search Results

1

Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy.

Zhang Y, Du X, Liu M, Tang F, Zhang P, Ai C, Fields JK, Sundberg EJ, Latinovic OS, Devenport M, Zheng P, Liu Y. Zhang Y, et al. Among authors: du x. Cell Res. 2019 Aug;29(8):609-627. doi: 10.1038/s41422-019-0184-1. Epub 2019 Jul 2. Cell Res. 2019. PMID: 31267017 Free PMC article.

2

The tumor immunosuppressive microenvironment impairs the therapy of anti-HER2/neu antibody.

Xu M, Du X, Liu M, Li S, Li X, Fu YX, Wang S. Xu M, et al. Among authors: du x. Protein Cell. 2012 Jun;3(6):441-9. doi: 10.1007/s13238-012-2044-3. Epub 2012 Jun 20. Protein Cell. 2012. PMID: 22717982 Free PMC article.

3

Uncoupling therapeutic from immunotherapy-related adverse effects for safer and effective anti-CTLA-4 antibodies in CTLA4 humanized mice.

Du X, Liu M, Su J, Zhang P, Tang F, Ye P, Devenport M, Wang X, Zhang Y, Liu Y, Zheng P. Du X, et al. Cell Res. 2018 Apr;28(4):433-447. doi: 10.1038/s41422-018-0012-z. Epub 2018 Feb 20. Cell Res. 2018. PMID: 29463898 Free PMC article.

4

A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy.

Du X, Tang F, Liu M, Su J, Zhang Y, Wu W, Devenport M, Lazarski CA, Zhang P, Wang X, Ye P, Wang C, Hwang E, Zhu T, Xu T, Zheng P, Liu Y. Du X, et al. Cell Res. 2018 Apr;28(4):416-432. doi: 10.1038/s41422-018-0011-0. Epub 2018 Feb 22. Cell Res. 2018. PMID: 29472691 Free PMC article.

5

Anti-CTLA-4 antibodies in cancer immunotherapy: selective depletion of intratumoral regulatory T cells or checkpoint blockade?

Tang F, Du X, Liu M, Zheng P, Liu Y. Tang F, et al. Among authors: du x. Cell Biosci. 2018 Apr 18;8:30. doi: 10.1186/s13578-018-0229-z. eCollection 2018. Cell Biosci. 2018. PMID: 29713453 Free PMC article.

6

Mechanism- and Immune Landscape-Based Ranking of Therapeutic Responsiveness of 22 Major Human Cancers to Next Generation Anti-CTLA-4 Antibodies.

Zhang P, Xiong X, Rolfo C, Du X, Zhang Y, Yang H, Russo A, Devenport M, Zhou P, Liu Y, Zheng P. Zhang P, et al. Among authors: du x. Cancers (Basel). 2020 Jan 24;12(2):284. doi: 10.3390/cancers12020284. Cancers (Basel). 2020. PMID: 31991588 Free PMC article.

7

Targeting HIF-1α abrogates PD-L1-mediated immune evasion in tumor microenvironment but promotes tolerance in normal tissues.

Bailey CM, Liu Y, Liu M, Du X, Devenport M, Zheng P, Liu Y, Wang Y. Bailey CM, et al. Among authors: du x. J Clin Invest. 2022 May 2;132(9):e150846. doi: 10.1172/JCI150846. J Clin Invest. 2022. PMID: 35239514 Free PMC article.

8

CD24Fc ameliorates immune-related adverse events while preserving anti-tumor therapeutic effect.

Liu M, Wang X, Du X, Zhang Y, Ai C, Hu-Lieskovan S, Li T, Devenport M, Liu Y, Zheng P. Liu M, et al. Among authors: du x. Signal Transduct Target Ther. 2022 Jul 15;7(1):224. doi: 10.1038/s41392-022-01030-x. Signal Transduct Target Ther. 2022. PMID: 35835736 Free PMC article. No abstract available.

9

CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.

Wang X, Liu M, Zhang J, Brown NK, Zhang P, Zhang Y, Liu H, Du X, Wu W, Devenport M, Tao W, Mao-Draayer Y, Chen GY, Chen YE, Zheng P, Liu Y. Wang X, et al. Among authors: du x. Cell Metab. 2022 Aug 2;34(8):1088-1103.e6. doi: 10.1016/j.cmet.2022.07.005. Cell Metab. 2022. PMID: 35921817 Free PMC article.

10

Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4- and PD-1-targeted immunotherapy.

Liu M, Wang X, Du X, Wu W, Zhang Y, Zhang P, Ai C, Devenport M, Su J, Muthana MM, Su L, Liu Y, Zheng P. Liu M, et al. Among authors: du x. Sci Transl Med. 2023 Mar;15(685):eabm5663. doi: 10.1126/scitranslmed.abm5663. Epub 2023 Mar 1. Sci Transl Med. 2023. PMID: 36857433 Free PMC article.

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