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137 results

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Page 1
Hsc70 rapidly engages tau after microtubule destabilization.
Jinwal UK, O'Leary JC 3rd, Borysov SI, Jones JR, Li Q, Koren J 3rd, Abisambra JF, Vestal GD, Lawson LY, Johnson AG, Blair LJ, Jin Y, Miyata Y, Gestwicki JE, Dickey CA. Jinwal UK, et al. Among authors: dickey ca. J Biol Chem. 2010 May 28;285(22):16798-805. doi: 10.1074/jbc.M110.113753. Epub 2010 Mar 22. J Biol Chem. 2010. PMID: 20308058 Free PMC article.
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.
Abisambra JF, Blair LJ, Hill SE, Jones JR, Kraft C, Rogers J, Koren J 3rd, Jinwal UK, Lawson L, Johnson AG, Wilcock D, O'Leary JC, Jansen-West K, Muschol M, Golde TE, Weeber EJ, Banko J, Dickey CA. Abisambra JF, et al. Among authors: dickey ca. J Neurosci. 2010 Nov 17;30(46):15374-82. doi: 10.1523/JNEUROSCI.3155-10.2010. J Neurosci. 2010. PMID: 21084594 Free PMC article.
DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau.
Abisambra JF, Jinwal UK, Suntharalingam A, Arulselvam K, Brady S, Cockman M, Jin Y, Zhang B, Dickey CA. Abisambra JF, et al. Among authors: dickey ca. J Mol Biol. 2012 Aug 24;421(4-5):653-61. doi: 10.1016/j.jmb.2012.02.003. Epub 2012 Feb 15. J Mol Biol. 2012. PMID: 22343013 Free PMC article.
Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism.
Suntharalingam A, Abisambra JF, O'Leary JC 3rd, Koren J 3rd, Zhang B, Joe MK, Blair LJ, Hill SE, Jinwal UK, Cockman M, Duerfeldt AS, Tomarev S, Blagg BS, Lieberman RL, Dickey CA. Suntharalingam A, et al. Among authors: dickey ca. J Biol Chem. 2012 Nov 23;287(48):40661-9. doi: 10.1074/jbc.M112.384800. Epub 2012 Oct 3. J Biol Chem. 2012. PMID: 23035116 Free PMC article.
Ligands for glaucoma-associated myocilin discovered by a generic binding assay.
Orwig SD, Chi PV, Du Y, Hill SE, Cavitt MA, Suntharalingam A, Turnage KC, Dickey CA, France S, Fu H, Lieberman RL. Orwig SD, et al. Among authors: dickey ca. ACS Chem Biol. 2014 Feb 21;9(2):517-25. doi: 10.1021/cb4007776. Epub 2013 Dec 9. ACS Chem Biol. 2014. PMID: 24279319 Free PMC article.
Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance.
Martin MD, Calcul L, Smith C, Jinwal UK, Fontaine SN, Darling A, Seeley K, Wojtas L, Narayan M, Gestwicki JE, Smith GR, Reitz AB, Baker BJ, Dickey CA. Martin MD, et al. Among authors: dickey ca. ACS Chem Biol. 2015 Apr 17;10(4):1099-109. doi: 10.1021/cb501013w. Epub 2015 Jan 30. ACS Chem Biol. 2015. PMID: 25588114 Free PMC article.
Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement.
Fontaine SN, Rauch JN, Nordhues BA, Assimon VA, Stothert AR, Jinwal UK, Sabbagh JJ, Chang L, Stevens SM Jr, Zuiderweg ER, Gestwicki JE, Dickey CA. Fontaine SN, et al. Among authors: dickey ca. J Biol Chem. 2015 May 22;290(21):13115-27. doi: 10.1074/jbc.M115.637595. Epub 2015 Apr 11. J Biol Chem. 2015. PMID: 25864199 Free PMC article.
137 results