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Bis(het)aryl-1,2,3-triazole quinuclidines as α7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [18F]-radiolabeling and PET study in rats.
Ouach A, Vercouillie J, Bertrand E, Rodrigues N, Pin F, Serriere S, Boiaryna L, Chartier A, Percina N, Tangpong P, Gulhan Z, Mothes C, Deloye JB, Guilloteau D, Page G, Suzenet F, Buron F, Chalon S, Routier S. Ouach A, et al. Among authors: deloye jb. Eur J Med Chem. 2019 Oct 1;179:449-469. doi: 10.1016/j.ejmech.2019.06.049. Epub 2019 Jun 27. Eur J Med Chem. 2019. PMID: 31271958
Design of α7 nicotinic acetylcholine receptor ligands in quinuclidine, tropane and quinazoline series. Chemistry, molecular modeling, radiochemistry, in vitro and in rats evaluations of a [(18)F] quinuclidine derivative.
Pin F, Vercouillie J, Ouach A, Mavel S, Gulhan Z, Chicheri G, Jarry C, Massip S, Deloye JB, Guilloteau D, Suzenet F, Chalon S, Routier S. Pin F, et al. Among authors: deloye jb. Eur J Med Chem. 2014 Jul 23;82:214-24. doi: 10.1016/j.ejmech.2014.04.057. Epub 2014 May 9. Eur J Med Chem. 2014. PMID: 24904968
Design of selective COX-2 inhibitors in the (aza)indazole series. Chemistry, in vitro studies, radiochemistry and evaluations in rats of a [18F] PET tracer.
Elie J, Vercouillie J, Arlicot N, Lemaire L, Bidault R, Bodard S, Hosselet C, Deloye JB, Chalon S, Emond P, Guilloteau D, Buron F, Routier S. Elie J, et al. Among authors: deloye jb. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1-7. doi: 10.1080/14756366.2018.1501043. J Enzyme Inhib Med Chem. 2019. PMID: 30362376 Free PMC article.
Extensive exploration of a novel rat model of Parkinson's disease using partial 6-hydroxydopamine lesion of dopaminergic neurons suggests new therapeutic approaches.
Vetel S, Sérrière S, Vercouillie J, Vergote J, Chicheri G, Deloye JB, Dollé F, Bodard S, Tronel C, Nadal-Desbarats L, Lefèvre A, Emond P, Chalon S. Vetel S, et al. Among authors: deloye jb. Synapse. 2019 Mar;73(3):e22077. doi: 10.1002/syn.22077. Epub 2018 Nov 12. Synapse. 2019. PMID: 30368914 Free article.
The Story of the Dopamine Transporter PET Tracer LBT-999: From Conception to Clinical Use.
Chalon S, Vercouillie J, Payoux P, Deloye JB, Malherbe C, Le Jeune F, Arlicot N, Salabert AS, Guilloteau D, Emond P, Ribeiro MJ. Chalon S, et al. Among authors: deloye jb. Front Med (Lausanne). 2019 May 3;6:90. doi: 10.3389/fmed.2019.00090. eCollection 2019. Front Med (Lausanne). 2019. PMID: 31131278 Free PMC article. Review.
Fully automated radiosynthesis of [18F]LBT999 on TRACERlab FXFN and AllinOne modules, a PET radiopharmaceutical for imaging the dopamine transporter in human brain.
Vala C, Mothes C, Chicheri G, Magadur P, Viot G, Deloye JB, Maia S, Bouvet Y, Dupont AC, Arlicot N, Guilloteau D, Emond P, Vercouillie J. Vala C, et al. Among authors: deloye jb. EJNMMI Radiopharm Chem. 2020 Nov 16;5(1):26. doi: 10.1186/s41181-020-00105-w. EJNMMI Radiopharm Chem. 2020. PMID: 33196944 Free PMC article.
16 results