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261,953 results

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Synthesis and evaluation of 4-halogeno-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-[11C]methylbenzamide for imaging of metabotropic glutamate 1 receptor in melanoma.
Fujinaga M, Xie L, Yamasaki T, Yui J, Shimoda Y, Hatori A, Kumata K, Zhang Y, Nengaki N, Kawamura K, Zhang MR. Fujinaga M, et al. Among authors: zhang mr, zhang y. J Med Chem. 2015 Feb 12;58(3):1513-23. doi: 10.1021/jm501845n. Epub 2015 Jan 30. J Med Chem. 2015. PMID: 25602363
Radiosynthesis and preliminary PET evaluation of glycogen synthase kinase 3β (GSK-3β) inhibitors containing [(11)C]methylsulfanyl, [(11)C]methylsulfinyl or [(11)C]methylsulfonyl groups.
Kumata K, Yui J, Xie L, Zhang Y, Nengaki N, Fujinaga M, Yamasaki T, Shimoda Y, Zhang MR. Kumata K, et al. Among authors: zhang mr, zhang y. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3230-3. doi: 10.1016/j.bmcl.2015.05.085. Epub 2015 Jun 3. Bioorg Med Chem Lett. 2015. PMID: 26067173
[18F]FEBMP: Positron Emission Tomography Imaging of TSPO in a Model of Neuroinflammation in Rats, and in vitro Autoradiograms of the Human Brain.
Tiwari AK, Ji B, Yui J, Fujinaga M, Yamasaki T, Xie L, Luo R, Shimoda Y, Kumata K, Zhang Y, Hatori A, Maeda J, Higuchi M, Wang F, Zhang MR. Tiwari AK, et al. Among authors: zhang mr, zhang y. Theranostics. 2015 May 26;5(9):961-9. doi: 10.7150/thno.12027. eCollection 2015. Theranostics. 2015. PMID: 26155312 Free PMC article.
Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on α-Ketoheterocyclic Scaffold.
Wang L, Yui J, Wang Q, Zhang Y, Mori W, Shimoda Y, Fujinaga M, Kumata K, Yamasaki T, Hatori A, Rotstein BH, Collier TL, Ran C, Vasdev N, Zhang MR, Liang SH. Wang L, et al. Among authors: zhang mr, zhang y. ACS Chem Neurosci. 2016 Jan 20;7(1):109-18. doi: 10.1021/acschemneuro.5b00248. Epub 2015 Nov 17. ACS Chem Neurosci. 2016. PMID: 26505525 Free PMC article.
Radiosynthesis and evaluation of 5-methyl-N-(4-[(11)C]methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine ([(11)C]ADX88178) as a novel radioligand for imaging of metabotropic glutamate receptor subtype 4 (mGluR4).
Fujinaga M, Yamasaki T, Nengaki N, Ogawa M, Kumata K, Shimoda Y, Yui J, Xie L, Zhang Y, Kawamura K, Zhang MR. Fujinaga M, et al. Among authors: zhang mr, zhang y. Bioorg Med Chem Lett. 2016 Jan 15;26(2):370-374. doi: 10.1016/j.bmcl.2015.12.008. Epub 2015 Dec 7. Bioorg Med Chem Lett. 2016. PMID: 26707390
N-(3,4-Dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[(11)C]methylphenyl)thiazol-2-yl]-1-carboxamide: A promising positron emission tomography ligand for fatty acid amide hydrolase.
Shimoda Y, Fujinaga M, Hatori A, Yui J, Zhang Y, Nengaki N, Kurihara Y, Yamasaki T, Xie L, Kumata K, Ishii H, Zhang MR. Shimoda Y, et al. Among authors: zhang mr, zhang y. Bioorg Med Chem. 2016 Feb 15;24(4):627-34. doi: 10.1016/j.bmc.2015.12.026. Epub 2015 Dec 15. Bioorg Med Chem. 2016. PMID: 26740152
Synthesis and Evaluation of Novel Radioligands Based on 3-[5-(Pyridin-2-yl)-2H-tetrazol-2-yl]benzonitrile for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor Subtype 5.
Shimoda Y, Yamasaki T, Fujinaga M, Ogawa M, Kurihara Y, Nengaki N, Kumata K, Yui J, Hatori A, Xie L, Zhang Y, Kawamura K, Zhang MR. Shimoda Y, et al. Among authors: zhang mr, zhang y. J Med Chem. 2016 Apr 28;59(8):3980-90. doi: 10.1021/acs.jmedchem.6b00209. Epub 2016 Apr 13. J Med Chem. 2016. PMID: 27015128
Efficient radiosynthesis and non-clinical safety tests of the TSPO radioprobe [(18)F]FEDAC: Prerequisites for clinical application.
Kawamura K, Kumata K, Takei M, Furutsuka K, Hashimoto H, Ito T, Shiomi S, Fujishiro T, Watanabe R, Igarashi N, Muto M, Yamasaki T, Yui J, Xie L, Hatori A, Zhang Y, Nemoto K, Fujibayashi Y, Zhang MR. Kawamura K, et al. Among authors: zhang mr, zhang y. Nucl Med Biol. 2016 Jul;43(7):445-53. doi: 10.1016/j.nucmedbio.2016.04.004. Epub 2016 Apr 26. Nucl Med Biol. 2016. PMID: 27183465
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