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The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases.
Roatsch M, Hoffmann I, Abboud MI, Hancock RL, Tarhonskaya H, Hsu KF, Wilkins SE, Yeh TL, Lippl K, Serrer K, Moneke I, Ahrens TD, Robaa D, Wenzler S, Barthes NPF, Franz H, Sippl W, Lassmann S, Diederichs S, Schleicher E, Schofield CJ, Kawamura A, Schüle R, Jung M. Roatsch M, et al. Among authors: abboud mi. ACS Chem Biol. 2019 Aug 16;14(8):1737-1750. doi: 10.1021/acschembio.9b00289. Epub 2019 Jul 19. ACS Chem Biol. 2019. PMID: 31287655
Targeting Protein-Protein Interactions in the HIF System.
Wilkins SE, Abboud MI, Hancock RL, Schofield CJ. Wilkins SE, et al. Among authors: abboud mi. ChemMedChem. 2016 Apr 19;11(8):773-86. doi: 10.1002/cmdc.201600012. Epub 2016 Mar 21. ChemMedChem. 2016. PMID: 26997519 Free PMC article. Review.
Normal tissue radioprotection by amifostine via Warburg-type effects.
Koukourakis MI, Giatromanolaki A, Zois CE, Kalamida D, Pouliliou S, Karagounis IV, Yeh TL, Abboud MI, Claridge TD, Schofield CJ, Sivridis E, Simopoulos C, Tokmakidis SP, Harris AL. Koukourakis MI, et al. Among authors: abboud mi. Sci Rep. 2016 Aug 10;6:30986. doi: 10.1038/srep30986. Sci Rep. 2016. PMID: 27507219 Free PMC article. Clinical Trial.
45 results