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KSK19 - Novel histamine H3 receptor ligand reduces body weight in diet induced obese mice.
Kotańska M, Mika K, Reguła K, Szczepańska K, Szafarz M, Bednarski M, Olejarz-Maciej A, Nowak K, Latacz G, Mogilski S, Kuder KJ, Kieć-Kononowicz K, Sapa J. Kotańska M, et al. Among authors: mika k. Biochem Pharmacol. 2019 Oct;168:193-203. doi: 10.1016/j.bcp.2019.07.006. Epub 2019 Jul 8. Biochem Pharmacol. 2019. PMID: 31295465
Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer's Disease.
Więckowska A, Wichur T, Godyń J, Bucki A, Marcinkowska M, Siwek A, Więckowski K, Zaręba P, Knez D, Głuch-Lutwin M, Kazek G, Latacz G, Mika K, Kołaczkowski M, Korabecny J, Soukup O, Benkova M, Kieć-Kononowicz K, Gobec S, Malawska B. Więckowska A, et al. Among authors: mika k. ACS Chem Neurosci. 2018 May 16;9(5):1195-1214. doi: 10.1021/acschemneuro.8b00024. Epub 2018 Feb 13. ACS Chem Neurosci. 2018. PMID: 29384656
Structural modifications and in vitro pharmacological evaluation of 4-pyridyl-piperazine derivatives as an active and selective histamine H3 receptor ligands.
Szczepańska K, Karcz T, Siwek A, Kuder KJ, Latacz G, Bednarski M, Szafarz M, Hagenow S, Lubelska A, Olejarz-Maciej A, Sobolewski M, Mika K, Kotańska M, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: mika k. Bioorg Chem. 2019 Oct;91:103071. doi: 10.1016/j.bioorg.2019.103071. Epub 2019 Jun 20. Bioorg Chem. 2019. PMID: 31362197
KD-64-A new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist-Caffeine does not reduce diet-induced obesity in mice.
Kotańska M, Dziubina A, Szafarz M, Mika K, Reguła K, Bednarski M, Zygmunt M, Drabczyńska A, Sapa J, Kieć-Kononowicz K. Kotańska M, et al. Among authors: mika k. PLoS One. 2020 Jun 18;15(6):e0229806. doi: 10.1371/journal.pone.0229806. eCollection 2020. PLoS One. 2020. PMID: 32555600 Free PMC article.
Structural modifications in the distal, regulatory region of histamine H3 receptor antagonists leading to the identification of a potent anti-obesity agent.
Szczepańska K, Pockes S, Podlewska S, Höring C, Mika K, Latacz G, Bednarski M, Siwek A, Karcz T, Nagl M, Bresinsky M, Mönnich D, Seibel U, Kuder KJ, Kotańska M, Stark H, Elz S, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: mika k. Eur J Med Chem. 2021 Mar 5;213:113041. doi: 10.1016/j.ejmech.2020.113041. Epub 2020 Nov 24. Eur J Med Chem. 2021. PMID: 33261900
66 results