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The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis.
Janes J, Young ME, Chen E, Rogers NH, Burgstaller-Muehlbacher S, Hughes LD, Love MS, Hull MV, Kuhen KL, Woods AK, Joseph SB, Petrassi HM, McNamara CW, Tremblay MS, Su AI, Schultz PG, Chatterjee AK. Janes J, et al. Among authors: hull mv. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10750-10755. doi: 10.1073/pnas.1810137115. Epub 2018 Oct 3. Proc Natl Acad Sci U S A. 2018. PMID: 30282735 Free PMC article.
Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.
Bakowski MA, Shiroodi RK, Liu R, Olejniczak J, Yang B, Gagaring K, Guo H, White PM, Chappell L, Debec A, Landmann F, Dubben B, Lenz F, Struever D, Ehrens A, Frohberger SJ, Sjoberg H, Pionnier N, Murphy E, Archer J, Steven A, Chunda VC, Fombad FF, Chounna PW, Njouendou AJ, Metuge HM, Ndzeshang BL, Gandjui NV, Akumtoh DN, Kwenti TDB, Woods AK, Joseph SB, Hull MV, Xiong W, Kuhen KL, Taylor MJ, Wanji S, Turner JD, Hübner MP, Hoerauf A, Chatterjee AK, Roland J, Tremblay MS, Schultz PG, Sullivan W, Chu XJ, Petrassi HM, McNamara CW. Bakowski MA, et al. Among authors: hull mv. Sci Transl Med. 2019 May 8;11(491):eaav3523. doi: 10.1126/scitranslmed.aav3523. Sci Transl Med. 2019. PMID: 31068442
Small-Molecule Stimulators of NRF1 Transcriptional Activity.
Iaconelli J, Ibrahim L, Chen E, Hull M, Schultz PG, Bollong MJ. Iaconelli J, et al. Chembiochem. 2020 Jul 1;21(13):1816-1819. doi: 10.1002/cbic.201900487. Epub 2019 Nov 8. Chembiochem. 2020. PMID: 31596542
Cell-Based Ligand Discovery for the ENL YEATS Domain.
Asiaban JN, Milosevich N, Chen E, Bishop TR, Wang J, Zhang Y, Ackerman CJ, Hampton EN, Young TS, Hull MV, Cravatt BF, Erb MA. Asiaban JN, et al. Among authors: hull mv. ACS Chem Biol. 2020 Apr 17;15(4):895-903. doi: 10.1021/acschembio.0c00124. Epub 2020 Mar 19. ACS Chem Biol. 2020. PMID: 32176478 Free PMC article.
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.
Riva L, Yuan S, Yin X, Martin-Sancho L, Matsunaga N, Pache L, Burgstaller-Muehlbacher S, De Jesus PD, Teriete P, Hull MV, Chang MW, Chan JF, Cao J, Poon VK, Herbert KM, Cheng K, Nguyen TH, Rubanov A, Pu Y, Nguyen C, Choi A, Rathnasinghe R, Schotsaert M, Miorin L, Dejosez M, Zwaka TP, Sit KY, Martinez-Sobrido L, Liu WC, White KM, Chapman ME, Lendy EK, Glynne RJ, Albrecht R, Ruppin E, Mesecar AD, Johnson JR, Benner C, Sun R, Schultz PG, Su AI, García-Sastre A, Chatterjee AK, Yuen KY, Chanda SK. Riva L, et al. Among authors: hull mv. Nature. 2020 Oct;586(7827):113-119. doi: 10.1038/s41586-020-2577-1. Epub 2020 Jul 24. Nature. 2020. PMID: 32707573 Free PMC article.
37 results