Nguyen T - Search Results

1

Phase I Study of Sorafenib and Vorinostat in Advanced Hepatocellular Carcinoma.

Gordon SW, McGuire WP 3rd, Shafer DA, Sterling RK, Lee HM, Matherly SC, Roberts JD, Bose P, Tombes MB, Shrader EE, Ryan AA, Kmieciak M, Nguyen T, Deng X, Bandyopadhyay D, Dent P, Poklepovic AS. Gordon SW, et al. Among authors: nguyen t. Am J Clin Oncol. 2019 Aug;42(8):649-654. doi: 10.1097/COC.0000000000000567. Am J Clin Oncol. 2019. PMID: 31305287 Clinical Trial.

2

Adaphostin and bortezomib induce oxidative injury and apoptosis in imatinib mesylate-resistant hematopoietic cells expressing mutant forms of Bcr/Abl.

Dasmahapatra G, Nguyen TK, Dent P, Grant S. Dasmahapatra G, et al. Leuk Res. 2006 Oct;30(10):1263-72. doi: 10.1016/j.leukres.2006.01.005. Epub 2006 Feb 14. Leuk Res. 2006. PMID: 16481037

3

Synergistic interactions between DMAG and mitogen-activated protein kinase kinase 1/2 inhibitors in Bcr/abl+ leukemia cells sensitive and resistant to imatinib mesylate.

Nguyen TK, Rahmani M, Gao N, Kramer L, Corbin AS, Druker BJ, Dent P, Grant S. Nguyen TK, et al. Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2239-47. doi: 10.1158/1078-0432.CCR-05-2282. Clin Cancer Res. 2006. PMID: 16609040

4

MEK1/2 inhibitors sensitize Bcr/Abl+ human leukemia cells to the dual Abl/Src inhibitor BMS-354/825.

Nguyen TK, Rahmani M, Harada H, Dent P, Grant S. Nguyen TK, et al. Blood. 2007 May 1;109(9):4006-15. doi: 10.1182/blood-2006-09-045039. Epub 2007 Jan 11. Blood. 2007. PMID: 17218385 Free PMC article. Clinical Trial.

5

The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress.

Rahmani M, Davis EM, Crabtree TR, Habibi JR, Nguyen TK, Dent P, Grant S. Rahmani M, et al. Mol Cell Biol. 2007 Aug;27(15):5499-513. doi: 10.1128/MCB.01080-06. Epub 2007 Jun 4. Mol Cell Biol. 2007. PMID: 17548474 Free PMC article.

6

The multikinase inhibitor sorafenib induces apoptosis in highly imatinib mesylate-resistant bcr/abl+ human leukemia cells in association with signal transducer and activator of transcription 5 inhibition and myeloid cell leukemia-1 down-regulation.

Rahmani M, Nguyen TK, Dent P, Grant S. Rahmani M, et al. Mol Pharmacol. 2007 Sep;72(3):788-95. doi: 10.1124/mol.106.033308. Epub 2007 Jun 26. Mol Pharmacol. 2007. PMID: 17595328

7

Vorinostat synergistically potentiates MK-0457 lethality in chronic myelogenous leukemia cells sensitive and resistant to imatinib mesylate.

Dai Y, Chen S, Venditti CA, Pei XY, Nguyen TK, Dent P, Grant S. Dai Y, et al. Blood. 2008 Aug 1;112(3):793-804. doi: 10.1182/blood-2007-10-116376. Epub 2008 May 27. Blood. 2008. PMID: 18505786 Free PMC article.

8

Inhibition of MEK/ERK1/2 sensitizes lymphoma cells to sorafenib-induced apoptosis.

Nguyen TK, Jordan N, Friedberg J, Fisher RI, Dent P, Grant S. Nguyen TK, et al. Leuk Res. 2010 Mar;34(3):379-86. doi: 10.1016/j.leukres.2009.07.013. Epub 2010 Feb 1. Leuk Res. 2010. PMID: 20117835 Free PMC article.

9

Synergism between bosutinib (SKI-606) and the Chk1 inhibitor (PF-00477736) in highly imatinib-resistant BCR/ABL⁺ leukemia cells.

Nguyen T, Hawkins E, Kolluri A, Kmieciak M, Park H, Lin H, Grant S. Nguyen T, et al. Leuk Res. 2015 Jan;39(1):65-71. doi: 10.1016/j.leukres.2014.10.009. Epub 2014 Nov 11. Leuk Res. 2015. PMID: 25465126 Free PMC article.

10

Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin's lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms.

Nguyen T, Parker R, Hawkins E, Holkova B, Yazbeck V, Kolluri A, Kmieciak M, Rahmani M, Grant S. Nguyen T, et al. Oncotarget. 2017 May 9;8(19):31478-31493. doi: 10.18632/oncotarget.15649. Oncotarget. 2017. PMID: 28416758 Free PMC article.

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