Wu Z - Search Results

1

AAVrh-10 transduces outer retinal cells in rodents and rabbits following intravitreal administration.

Zeng Y, Qian H, Wu Z, Marangoni D, Sieving PA, Bush RA. Zeng Y, et al. Among authors: wu z. Gene Ther. 2019 Sep;26(9):386-398. doi: 10.1038/s41434-019-0094-3. Epub 2019 Jul 15. Gene Ther. 2019. PMID: 31308478 Free PMC article.

2

Intravitreal delivery of AAV8 retinoschisin results in cell type-specific gene expression and retinal rescue in the Rs1-KO mouse.

Park TK, Wu Z, Kjellstrom S, Zeng Y, Bush RA, Sieving PA, Colosi P. Park TK, et al. Among authors: wu z. Gene Ther. 2009 Jul;16(7):916-26. doi: 10.1038/gt.2009.61. Epub 2009 May 21. Gene Ther. 2009. PMID: 19458650 Free PMC article.

3

Preclinical safety evaluation of a recombinant AAV8 vector for X-linked retinoschisis after intravitreal administration in rabbits.

Marangoni D, Wu Z, Wiley HE, Zeiss CJ, Vijayasarathy C, Zeng Y, Hiriyanna S, Bush RA, Wei LL, Colosi P, Sieving PA. Marangoni D, et al. Among authors: wu z. Hum Gene Ther Clin Dev. 2014 Dec;25(4):202-11. doi: 10.1089/humc.2014.067. Hum Gene Ther Clin Dev. 2014. PMID: 25211193 Free PMC article.

4

Preclinical Dose-Escalation Study of Intravitreal AAV-RS1 Gene Therapy in a Mouse Model of X-linked Retinoschisis: Dose-Dependent Expression and Improved Retinal Structure and Function.

Bush RA, Zeng Y, Colosi P, Kjellstrom S, Hiriyanna S, Vijayasarathy C, Santos M, Li J, Wu Z, Sieving PA. Bush RA, et al. Among authors: wu z. Hum Gene Ther. 2016 May;27(5):376-89. doi: 10.1089/hum.2015.142. Hum Gene Ther. 2016. PMID: 27036983 Free PMC article.

5

Retinal AAV8-RS1 Gene Therapy for X-Linked Retinoschisis: Initial Findings from a Phase I/IIa Trial by Intravitreal Delivery.

Cukras C, Wiley HE, Jeffrey BG, Sen HN, Turriff A, Zeng Y, Vijayasarathy C, Marangoni D, Ziccardi L, Kjellstrom S, Park TK, Hiriyanna S, Wright JF, Colosi P, Wu Z, Bush RA, Wei LL, Sieving PA. Cukras C, et al. Among authors: wu z. Mol Ther. 2018 Sep 5;26(9):2282-2294. doi: 10.1016/j.ymthe.2018.05.025. Epub 2018 Jul 7. Mol Ther. 2018. PMID: 30196853 Free PMC article. Clinical Trial.

6

Trans-ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Gene Transduction after Intravitreal Vector Administration.

Song H, Bush RA, Zeng Y, Qian H, Wu Z, Sieving PA. Song H, et al. Among authors: wu z. Mol Ther Methods Clin Dev. 2018 Dec 21;13:77-85. doi: 10.1016/j.omtm.2018.12.006. eCollection 2019 Jun 14. Mol Ther Methods Clin Dev. 2018. PMID: 30719486 Free PMC article.

7

A Common Outer Retinal Change in Retinal Degeneration by Optical Coherence Tomography Can Be Used to Assess Outcomes of Gene Therapy.

Joe MK, Li W, Hiriyanna S, Yu W, Shah SA, Abu-Asab M, Qian H, Wu Z. Joe MK, et al. Among authors: wu z. Hum Gene Ther. 2019 Dec;30(12):1520-1530. doi: 10.1089/hum.2019.162. Epub 2019 Dec 4. Hum Gene Ther. 2019. PMID: 31672061 Free PMC article.

8

Trans-Ocular Electric Current In Vivo Enhances AAV-Mediated Retinal Transduction in Large Animal Eye After Intravitreal Vector Administration.

Song H, Zeng Y, Sardar Pasha SPB, Bush RA, Vijayasarathy C, Qian H, Wei L, Wiley HE, Wu Z, Sieving PA. Song H, et al. Among authors: wu z. Transl Vis Sci Technol. 2020 Jun 24;9(7):28. doi: 10.1167/tvst.9.7.28. eCollection 2020 Jun. Transl Vis Sci Technol. 2020. PMID: 32844051 Free PMC article.

9

A long-term efficacy study of gene replacement therapy for RPGR-associated retinal degeneration.

Wu Z, Hiriyanna S, Qian H, Mookherjee S, Campos MM, Gao C, Fariss R, Sieving PA, Li T, Colosi P, Swaroop A. Wu Z, et al. Hum Mol Genet. 2015 Jul 15;24(14):3956-70. doi: 10.1093/hmg/ddv134. Epub 2015 Apr 15. Hum Mol Genet. 2015. PMID: 25877300 Free PMC article.

10

NADPH Oxidase Contributes to Photoreceptor Degeneration in Constitutively Active RAC1 Mice.

Song H, Vijayasarathy C, Zeng Y, Marangoni D, Bush RA, Wu Z, Sieving PA. Song H, et al. Among authors: wu z. Invest Ophthalmol Vis Sci. 2016 May 1;57(6):2864-75. doi: 10.1167/iovs.15-18974. Invest Ophthalmol Vis Sci. 2016. PMID: 27233035 Free PMC article.

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