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Page 1
Anti-IL-13Rα2 therapy promotes recovery in a murine model of inflammatory bowel disease.
Karmele EP, Pasricha TS, Ramalingam TR, Thompson RW, Gieseck RL 3rd, Knilans KJ, Hegen M, Farmer M, Jin F, Kleinman A, Hinds DA; 23andMe Research Team; Almeida Pereira T, de Queiroz Prado R, Bing N, Tchistiakova L, Kasaian MT, Wynn TA, Vannella KM. Karmele EP, et al. Among authors: kleinman a. Mucosal Immunol. 2019 Sep;12(5):1174-1186. doi: 10.1038/s41385-019-0189-6. Epub 2019 Jul 15. Mucosal Immunol. 2019. PMID: 31308480 Free PMC article.
An atlas of genetic influences on osteoporosis in humans and mice.
Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, Simon MM, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum AT, Mannan NS, Komla-Ebri DSK, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar MG; 23andMe Research Team; Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani EE, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu YH, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB. Morris JA, et al. Among authors: kleinman a. Nat Genet. 2019 Feb;51(2):258-266. doi: 10.1038/s41588-018-0302-x. Epub 2018 Dec 31. Nat Genet. 2019. PMID: 30598549 Free PMC article.
Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci.
Dudding T, Haworth S, Lind PA, Sathirapongsasuti JF; 23andMe Research Team; Tung JY, Mitchell R, Colodro-Conde L, Medland SE, Gordon S, Elsworth B, Paternoster L, Franks PW, Thomas SJ, Martin NG, Timpson NJ. Dudding T, et al. Nat Commun. 2019 Mar 5;10(1):1052. doi: 10.1038/s41467-019-08923-6. Nat Commun. 2019. PMID: 30837455 Free PMC article.
Insights into the genetic basis of retinal detachment.
Boutin TS, Charteris DG, Chandra A, Campbell S, Hayward C, Campbell A; UK Biobank Eye & Vision Consortium; Nandakumar P, Hinds D; 23andMe Research Team; Mitry D, Vitart V. Boutin TS, et al. Hum Mol Genet. 2020 Mar 13;29(4):689-702. doi: 10.1093/hmg/ddz294. Hum Mol Genet. 2020. PMID: 31816047 Free PMC article.
The effect of LRRK2 loss-of-function variants in humans.
Whiffin N, Armean IM, Kleinman A, Marshall JL, Minikel EV, Goodrich JK, Quaife NM, Cole JB, Wang Q, Karczewski KJ, Cummings BB, Francioli L, Laricchia K, Guan A, Alipanahi B, Morrison P, Baptista MAS, Merchant KM; Genome Aggregation Database Production Team; Genome Aggregation Database Consortium; Ware JS, Havulinna AS, Iliadou B, Lee JJ, Nadkarni GN, Whiteman C; 23andMe Research Team; Daly M, Esko T, Hultman C, Loos RJF, Milani L, Palotie A, Pato C, Pato M, Saleheen D, Sullivan PF, Alföldi J, Cannon P, MacArthur DG. Whiffin N, et al. Among authors: kleinman a. Nat Med. 2020 Jun;26(6):869-877. doi: 10.1038/s41591-020-0893-5. Epub 2020 May 27. Nat Med. 2020. PMID: 32461697 Free PMC article.
314 results