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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment.
Zemek RM, De Jong E, Chin WL, Schuster IS, Fear VS, Casey TH, Forbes C, Dart SJ, Leslie C, Zaitouny A, Small M, Boon L, Forrest ARR, Muiri DO, Degli-Esposti MA, Millward MJ, Nowak AK, Lassmann T, Bosco A, Lake RA, Lesterhuis WJ. Zemek RM, et al. Among authors: schuster is. Sci Transl Med. 2019 Jul 17;11(501):eaav7816. doi: 10.1126/scitranslmed.aav7816. Sci Transl Med. 2019. PMID: 31316010 Free article.
A natural genetic variant of granzyme B confers lethality to a common viral infection.
Andoniou CE, Sutton VR, Wikstrom ME, Fleming P, Thia KY, Matthews AY, Kaiserman D, Schuster IS, Coudert JD, Eldi P, Chaudhri G, Karupiah G, Bird PI, Trapani JA, Degli-Esposti MA. Andoniou CE, et al. Among authors: schuster is. PLoS Pathog. 2014 Dec 11;10(12):e1004526. doi: 10.1371/journal.ppat.1004526. eCollection 2014 Dec. PLoS Pathog. 2014. PMID: 25502180 Free PMC article.
GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.
Bunting MD, Varelias A, Souza-Fonseca-Guimaraes F, Schuster IS, Lineburg KE, Kuns RD, Fleming P, Locke KR, Huntington ND, Blazar BR, Lane SW, Tey SK, MacDonald KP, Smyth MJ, Degli-Esposti MA, Hill GR. Bunting MD, et al. Among authors: schuster is. Blood. 2017 Feb 2;129(5):630-642. doi: 10.1182/blood-2016-08-734020. Epub 2016 Dec 7. Blood. 2017. PMID: 27927647 Free PMC article.
Eomesodermin promotes the development of type 1 regulatory T (TR1) cells.
Zhang P, Lee JS, Gartlan KH, Schuster IS, Comerford I, Varelias A, Ullah MA, Vuckovic S, Koyama M, Kuns RD, Locke KR, Beckett KJ, Olver SD, Samson LD, Montes de Oca M, de Labastida Rivera F, Clouston AD, Belz GT, Blazar BR, MacDonald KP, McColl SR, Thomas R, Engwerda CR, Degli-Esposti MA, Kallies A, Tey SK, Hill GR. Zhang P, et al. Among authors: schuster is. Sci Immunol. 2017 Apr 7;2(10):eaah7152. doi: 10.1126/sciimmunol.aah7152. Sci Immunol. 2017. PMID: 28738016 Free PMC article.
ILC1 Confer Early Host Protection at Initial Sites of Viral Infection.
Weizman OE, Adams NM, Schuster IS, Krishna C, Pritykin Y, Lau C, Degli-Esposti MA, Leslie CS, Sun JC, O'Sullivan TE. Weizman OE, et al. Among authors: schuster is. Cell. 2017 Nov 2;171(4):795-808.e12. doi: 10.1016/j.cell.2017.09.052. Epub 2017 Oct 19. Cell. 2017. PMID: 29056343 Free PMC article.
24 results