Hegedűs T - Search Results

1

Discovering the chloride pathway in the CFTR channel.

Farkas B, Tordai H, Padányi R, Tordai A, Gera J, Paragi G, Hegedűs T. Farkas B, et al. Among authors: hegedus t. Cell Mol Life Sci. 2020 Feb;77(4):765-778. doi: 10.1007/s00018-019-03211-4. Epub 2019 Jul 20. Cell Mol Life Sci. 2020. PMID: 31327045 Free PMC article.

2

HAEdb: a novel interactive, locus-specific mutation database for the C1 inhibitor gene.

Kalmár L, Hegedüs T, Farkas H, Nagy M, Tordai A. Kalmár L, et al. Among authors: hegedus t. Hum Mutat. 2005 Jan;25(1):1-5. doi: 10.1002/humu.20112. Hum Mutat. 2005. PMID: 15580551

3

Domain interdependence in the biosynthetic assembly of CFTR.

Cui L, Aleksandrov L, Chang XB, Hou YX, He L, Hegedus T, Gentzsch M, Aleksandrov A, Balch WE, Riordan JR. Cui L, et al. Among authors: hegedus t. J Mol Biol. 2007 Jan 26;365(4):981-94. doi: 10.1016/j.jmb.2006.10.086. Epub 2006 Nov 10. J Mol Biol. 2007. PMID: 17113596

4

Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function.

Serohijos AW, Hegedus T, Aleksandrov AA, He L, Cui L, Dokholyan NV, Riordan JR. Serohijos AW, et al. Among authors: hegedus t. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3256-61. doi: 10.1073/pnas.0800254105. Epub 2008 Feb 27. Proc Natl Acad Sci U S A. 2008. PMID: 18305154 Free PMC article.

5

Computational studies reveal phosphorylation-dependent changes in the unstructured R domain of CFTR.

Hegedus T, Serohijos AW, Dokholyan NV, He L, Riordan JR. Hegedus T, et al. J Mol Biol. 2008 May 16;378(5):1052-63. doi: 10.1016/j.jmb.2008.03.033. Epub 2008 Mar 26. J Mol Biol. 2008. PMID: 18423665 Free PMC article.

6

ABCMdb: a database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application.

Gyimesi G, Borsodi D, Sarankó H, Tordai H, Sarkadi B, Hegedűs T. Gyimesi G, et al. Among authors: hegedus t. Hum Mutat. 2012 Nov;33(11):1547-56. doi: 10.1002/humu.22138. Epub 2012 Jul 11. Hum Mutat. 2012. PMID: 22693078

7

Effects of the gout-causing Q141K polymorphism and a CFTR ΔF508 mimicking mutation on the processing and stability of the ABCG2 protein.

Sarankó H, Tordai H, Telbisz Á, Özvegy-Laczka C, Erdős G, Sarkadi B, Hegedűs T. Sarankó H, et al. Among authors: hegedus t. Biochem Biophys Res Commun. 2013 Jul 19;437(1):140-5. doi: 10.1016/j.bbrc.2013.06.054. Epub 2013 Jun 22. Biochem Biophys Res Commun. 2013. PMID: 23800412

8

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression.

Veit G, Avramescu RG, Perdomo D, Phuan PW, Bagdany M, Apaja PM, Borot F, Szollosi D, Wu YS, Finkbeiner WE, Hegedus T, Verkman AS, Lukacs GL. Veit G, et al. Among authors: hegedus t. Sci Transl Med. 2014 Jul 23;6(246):246ra97. doi: 10.1126/scitranslmed.3008889. Sci Transl Med. 2014. PMID: 25101887 Free PMC article.

9

The linker region of breast cancer resistance protein ABCG2 is critical for coupling of ATP-dependent drug transport.

Macalou S, Robey RW, Jabor Gozzi G, Shukla S, Grosjean I, Hegedus T, Ambudkar SV, Bates SE, Di Pietro A. Macalou S, et al. Among authors: hegedus t. Cell Mol Life Sci. 2016 May;73(9):1927-37. doi: 10.1007/s00018-015-2118-5. Epub 2015 Dec 26. Cell Mol Life Sci. 2016. PMID: 26708291 Free PMC article.

10

ABCMdb reloaded: updates on mutations in ATP binding cassette proteins.

Tordai H, Jakab K, Gyimesi G, András K, Brózik A, Sarkadi B, Hegedus T. Tordai H, et al. Among authors: hegedus t. Database (Oxford). 2017 Jan 1;2017(1):bax023. doi: 10.1093/database/bax023. Database (Oxford). 2017. PMID: 28365738 Free PMC article.

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