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The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice.
Debeuf N, Zhakupova A, Steiner R, Van Gassen S, Deswarte K, Fayazpour F, Van Moorleghem J, Vergote K, Pavie B, Lemeire K, Hammad H, Hornemann T, Janssens S, Lambrecht BN. Debeuf N, et al. Among authors: steiner r. J Allergy Clin Immunol. 2019 Dec;144(6):1648-1659.e9. doi: 10.1016/j.jaci.2019.06.041. Epub 2019 Jul 20. J Allergy Clin Immunol. 2019. PMID: 31330218 Free PMC article.
Sphingosine 1-phosphate lyase deficiency causes Charcot-Marie-Tooth neuropathy.
Atkinson D, Nikodinovic Glumac J, Asselbergh B, Ermanoska B, Blocquel D, Steiner R, Estrada-Cuzcano A, Peeters K, Ooms T, De Vriendt E, Yang XL, Hornemann T, Milic Rasic V, Jordanova A. Atkinson D, et al. Among authors: steiner r. Neurology. 2017 Feb 7;88(6):533-542. doi: 10.1212/WNL.0000000000003595. Epub 2017 Jan 11. Neurology. 2017. PMID: 28077491 Free PMC article.
Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.
Storti F, Klee K, Todorova V, Steiner R, Othman A, van der Velde-Visser S, Samardzija M, Meneau I, Barben M, Karademir D, Pauzuolyte V, Boye SL, Blaser F, Ullmer C, Dunaief JL, Hornemann T, Rohrer L, den Hollander A, von Eckardstein A, Fingerle J, Maugeais C, Grimm C. Storti F, et al. Among authors: steiner r. Elife. 2019 Mar 13;8:e45100. doi: 10.7554/eLife.45100. Elife. 2019. PMID: 30864945 Free PMC article.
DEGS1-associated aberrant sphingolipid metabolism impairs nervous system function in humans.
Karsai G, Kraft F, Haag N, Korenke GC, Hänisch B, Othman A, Suriyanarayanan S, Steiner R, Knopp C, Mull M, Bergmann M, Schröder JM, Weis J, Elbracht M, Begemann M, Hornemann T, Kurth I. Karsai G, et al. Among authors: steiner r. J Clin Invest. 2019 Mar 1;129(3):1229-1239. doi: 10.1172/JCI124159. Epub 2019 Feb 11. J Clin Invest. 2019. PMID: 30620338 Free PMC article.
Elucidating the chemical structure of native 1-deoxysphingosine.
Steiner R, Saied EM, Othman A, Arenz C, Maccarone AT, Poad BL, Blanksby SJ, von Eckardstein A, Hornemann T. Steiner R, et al. J Lipid Res. 2016 Jul;57(7):1194-203. doi: 10.1194/jlr.M067033. Epub 2016 May 10. J Lipid Res. 2016. PMID: 27165858 Free PMC article.
Thiazole-based IL-17 inhibitors discovered by scaffold morphing.
Velcicky J, Ngo E, Bauer MR, Meyer A, Schlapbach A, Racine S, Orain D, Pflieger D, Teixeira-Fouchard S, Dubois C, Goetz A, Steiner R, Palmieri M, Bussenault A, Stringer R, Larger P, Riek S, Schmutz P, Lehmann S, Scheufler C, Rondeau JM, Burkhart C, Knoepfel T, Gommermann N. Velcicky J, et al. Among authors: steiner r. ChemMedChem. 2024 Dec 23:e202400851. doi: 10.1002/cmdc.202400851. Online ahead of print. ChemMedChem. 2024. PMID: 39715021
Effectiveness of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) as switch strategy in virologically-suppressed patients: real world data from a monocentric cohort.
Passerotto RA, Lamanna F, Salvo PF, Iannone V, Steiner RJ, Carbone A, Farinacci D, D'Angelillo A, Baldin G, Ciccullo A, Di Giambenedetto S, Torti C, Borghetti A. Passerotto RA, et al. Among authors: steiner rj. Antivir Ther. 2024 Dec;29(6):13596535241306467. doi: 10.1177/13596535241306467. Antivir Ther. 2024. PMID: 39698926 Free article.
1,749 results