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Both gain and loss of Nampt function promote pressure overload-induced heart failure.
Byun J, Oka SI, Imai N, Huang CY, Ralda G, Zhai P, Ikeda Y, Ikeda S, Sadoshima J. Byun J, et al. Among authors: ralda g. Am J Physiol Heart Circ Physiol. 2019 Oct 1;317(4):H711-H725. doi: 10.1152/ajpheart.00222.2019. Epub 2019 Jul 26. Am J Physiol Heart Circ Physiol. 2019. PMID: 31347918 Free PMC article.
Nampt Potentiates Antioxidant Defense in Diabetic Cardiomyopathy.
Oka SI, Byun J, Huang CY, Imai N, Ralda G, Zhai P, Xu X, Kashyap S, Warren JS, Alan Maschek J, Tippetts TS, Tong M, Venkatesh S, Ikeda Y, Mizushima W, Kashihara T, Sadoshima J. Oka SI, et al. Among authors: ralda g. Circ Res. 2021 Jun 25;129(1):114-130. doi: 10.1161/CIRCRESAHA.120.317943. Epub 2021 Apr 30. Circ Res. 2021. PMID: 33928788 Free PMC article.
Recruitment of RNA Polymerase II to Metabolic Gene Promoters Is Inhibited in the Failing Heart Possibly Through PGC-1α (Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α) Dysregulation.
Bhat S, Chin A, Shirakabe A, Ikeda Y, Ikeda S, Zhai P, Hsu CP, Sayed D, Abdellatif M, Byun J, Schesing K, Tang F, Tian Y, Babu G, Ralda G, Warren JS, Cho J, Sadoshima J, Oka SI. Bhat S, et al. Among authors: ralda g. Circ Heart Fail. 2019 Mar;12(3):e005529. doi: 10.1161/CIRCHEARTFAILURE.118.005529. Circ Heart Fail. 2019. PMID: 30798619 Free PMC article.