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Both gain and loss of Nampt function promote pressure overload-induced heart failure.
Byun J, Oka SI, Imai N, Huang CY, Ralda G, Zhai P, Ikeda Y, Ikeda S, Sadoshima J. Byun J, et al. Among authors: sadoshima j. Am J Physiol Heart Circ Physiol. 2019 Oct 1;317(4):H711-H725. doi: 10.1152/ajpheart.00222.2019. Epub 2019 Jul 26. Am J Physiol Heart Circ Physiol. 2019. PMID: 31347918 Free PMC article.
Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.
Zhai P, Yamamoto M, Galeotti J, Liu J, Masurekar M, Thaisz J, Irie K, Holle E, Yu X, Kupershmidt S, Roden DM, Wagner T, Yatani A, Vatner DE, Vatner SF, Sadoshima J. Zhai P, et al. Among authors: sadoshima j. J Clin Invest. 2005 Nov;115(11):3045-56. doi: 10.1172/JCI25330. J Clin Invest. 2005. PMID: 16276415 Free PMC article.
Sirt1 regulates aging and resistance to oxidative stress in the heart.
Alcendor RR, Gao S, Zhai P, Zablocki D, Holle E, Yu X, Tian B, Wagner T, Vatner SF, Sadoshima J. Alcendor RR, et al. Among authors: sadoshima j. Circ Res. 2007 May 25;100(10):1512-21. doi: 10.1161/01.RES.0000267723.65696.4a. Epub 2007 Apr 19. Circ Res. 2007. PMID: 17446436
Lats2 is a negative regulator of myocyte size in the heart.
Matsui Y, Nakano N, Shao D, Gao S, Luo W, Hong C, Zhai P, Holle E, Yu X, Yabuta N, Tao W, Wagner T, Nojima H, Sadoshima J. Matsui Y, et al. Among authors: sadoshima j. Circ Res. 2008 Nov 21;103(11):1309-18. doi: 10.1161/CIRCRESAHA.108.180042. Epub 2008 Oct 16. Circ Res. 2008. PMID: 18927464 Free PMC article.
400 results