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Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.
Leenay RT, Aghazadeh A, Hiatt J, Tse D, Roth TL, Apathy R, Shifrut E, Hultquist JF, Krogan N, Wu Z, Cirolia G, Canaj H, Leonetti MD, Marson A, May AP, Zou J. Leenay RT, et al. Among authors: aghazadeh a. Nat Biotechnol. 2019 Sep;37(9):1034-1037. doi: 10.1038/s41587-019-0203-2. Epub 2019 Jul 29. Nat Biotechnol. 2019. PMID: 31359007 Free PMC article.
Current progress and open challenges for applying deep learning across the biosciences.
Sapoval N, Aghazadeh A, Nute MG, Antunes DA, Balaji A, Baraniuk R, Barberan CJ, Dannenfelser R, Dun C, Edrisi M, Elworth RAL, Kille B, Kyrillidis A, Nakhleh L, Wolfe CR, Yan Z, Yao V, Treangen TJ. Sapoval N, et al. Among authors: aghazadeh a. Nat Commun. 2022 Apr 1;13(1):1728. doi: 10.1038/s41467-022-29268-7. Nat Commun. 2022. PMID: 35365602 Free PMC article. Review.
On the sparsity of fitness functions and implications for learning.
Brookes DH, Aghazadeh A, Listgarten J. Brookes DH, et al. Among authors: aghazadeh a. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2109649118. doi: 10.1073/pnas.2109649118. Proc Natl Acad Sci U S A. 2022. PMID: 34937698 Free PMC article.
Universal microbial diagnostics using random DNA probes.
Aghazadeh A, Lin AY, Sheikh MA, Chen AL, Atkins LM, Johnson CL, Petrosino JF, Drezek RA, Baraniuk RG. Aghazadeh A, et al. Sci Adv. 2016 Sep 28;2(9):e1600025. doi: 10.1126/sciadv.1600025. eCollection 2016 Sep. Sci Adv. 2016. PMID: 27704040 Free PMC article.
31 results