Grant BD - Search Results

1

Noncompetitive inhibitors of TNFR1 probe conformational activation states.

Lo CH, Schaaf TM, Grant BD, Lim CK, Bawaskar P, Aldrich CC, Thomas DD, Sachs JN. Lo CH, et al. Among authors: grant bd. Sci Signal. 2019 Jul 30;12(592):eaav5637. doi: 10.1126/scisignal.aav5637. Sci Signal. 2019. PMID: 31363069 Free PMC article.

2

An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors.

Lo CH, Vunnam N, Lewis AK, Chiu TL, Brummel BE, Schaaf TM, Grant BD, Bawaskar P, Thomas DD, Sachs JN. Lo CH, et al. Among authors: grant bd. SLAS Discov. 2017 Sep;22(8):950-961. doi: 10.1177/2472555217706478. Epub 2017 May 22. SLAS Discov. 2017. PMID: 28530838 Free PMC article.

3

Soluble Extracellular Domain of Death Receptor 5 Inhibits TRAIL-Induced Apoptosis by Disrupting Receptor-Receptor Interactions.

Vunnam N, Lo CH, Grant BD, Thomas DD, Sachs JN. Vunnam N, et al. Among authors: grant bd. J Mol Biol. 2017 Sep 15;429(19):2943-2953. doi: 10.1016/j.jmb.2017.08.009. Epub 2017 Aug 20. J Mol Biol. 2017. PMID: 28834692

4

Spectral Unmixing Plate Reader: High-Throughput, High-Precision FRET Assays in Living Cells.

Schaaf TM, Peterson KC, Grant BD, Thomas DD, Gillispie GD. Schaaf TM, et al. Among authors: grant bd. SLAS Discov. 2017 Mar;22(3):250-261. doi: 10.1177/1087057116679637. Epub 2016 Nov 23. SLAS Discov. 2017. PMID: 27879398 Free PMC article.

5

High-Throughput Spectral and Lifetime-Based FRET Screening in Living Cells to Identify Small-Molecule Effectors of SERCA.

Schaaf TM, Peterson KC, Grant BD, Bawaskar P, Yuen S, Li J, Muretta JM, Gillispie GD, Thomas DD. Schaaf TM, et al. Among authors: grant bd. SLAS Discov. 2017 Mar;22(3):262-273. doi: 10.1177/1087057116680151. Epub 2016 Dec 13. SLAS Discov. 2017. PMID: 27899691 Free PMC article.

6

Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening.

Schaaf TM, Li A, Grant BD, Peterson K, Yuen S, Bawaskar P, Kleinboehl E, Li J, Thomas DD, Gillispie GD. Schaaf TM, et al. Among authors: grant bd. Biosensors (Basel). 2018 Oct 24;8(4):99. doi: 10.3390/bios8040099. Biosensors (Basel). 2018. PMID: 30352972 Free PMC article.

7

High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin-myosin structure and function.

Guhathakurta P, Prochniewicz E, Grant BD, Peterson KC, Thomas DD. Guhathakurta P, et al. Among authors: grant bd. J Biol Chem. 2018 Aug 3;293(31):12288-12298. doi: 10.1074/jbc.RA118.002702. Epub 2018 Jun 4. J Biol Chem. 2018. PMID: 29866882 Free PMC article.

8

High-Throughput Screens to Discover Small-Molecule Modulators of Ryanodine Receptor Calcium Release Channels.

Rebbeck RT, Essawy MM, Nitu FR, Grant BD, Gillispie GD, Thomas DD, Bers DM, Cornea RL. Rebbeck RT, et al. Among authors: grant bd. SLAS Discov. 2017 Feb;22(2):176-186. doi: 10.1177/1087057116674312. Epub 2016 Oct 22. SLAS Discov. 2017. PMID: 27760856 Free PMC article.

9

Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons.

Wang G, Guasp RJ, Salam S, Chuang E, Morera A, Smart AJ, Jimenez D, Shekhar S, Friedman E, Melentijevic I, Nguyen KC, Hall DH, Grant BD, Driscoll M. Wang G, et al. Among authors: grant bd. Elife. 2024 Sep 10;13:RP95443. doi: 10.7554/eLife.95443. Elife. 2024. PMID: 39255003 Free PMC article.

10

RABR-1, an atypical Rab-related GTPase, cell-nonautonomously restricts somatosensory dendrite branching.

Salazar CJ, Diaz-Balzac CA, Wang Y, Rahman M, Grant BD, Bülow HE. Salazar CJ, et al. Among authors: grant bd. Genetics. 2024 Oct 7;228(2):iyae113. doi: 10.1093/genetics/iyae113. Genetics. 2024. PMID: 39028768

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