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mTOR Mediated Anti-Cancer Drug Discovery.
Liu Q, Thoreen C, Wang J, Sabatini D, Gray NS. Liu Q, et al. Among authors: gray ns. Drug Discov Today Ther Strateg. 2009 Summer;6(2):47-55. doi: 10.1016/j.ddstr.2009.12.001. Drug Discov Today Ther Strateg. 2009. PMID: 20622997 Free PMC article.
Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer.
Liu Q, Wang J, Kang SA, Thoreen CC, Hur W, Ahmed T, Sabatini DM, Gray NS. Liu Q, et al. Among authors: gray ns. J Med Chem. 2011 Mar 10;54(5):1473-80. doi: 10.1021/jm101520v. Epub 2011 Feb 15. J Med Chem. 2011. PMID: 21322566 Free PMC article.
Fluorescent visualization of Src by using dasatinib-BODIPY.
Vetter ML, Zhang Z, Liu S, Wang J, Cho H, Zhang J, Zhang W, Gray NS, Yang PL. Vetter ML, et al. Among authors: gray ns. Chembiochem. 2014 Jun 16;15(9):1317-24. doi: 10.1002/cbic.201402010. Epub 2014 May 14. Chembiochem. 2014. PMID: 24828915 Free PMC article.
Systematic identification of culture conditions for induction and maintenance of naive human pluripotency.
Theunissen TW, Powell BE, Wang H, Mitalipova M, Faddah DA, Reddy J, Fan ZP, Maetzel D, Ganz K, Shi L, Lungjangwa T, Imsoonthornruksa S, Stelzer Y, Rangarajan S, D'Alessio A, Zhang J, Gao Q, Dawlaty MM, Young RA, Gray NS, Jaenisch R. Theunissen TW, et al. Among authors: gray ns. Cell Stem Cell. 2014 Oct 2;15(4):471-487. doi: 10.1016/j.stem.2014.07.002. Epub 2014 Jul 24. Cell Stem Cell. 2014. PMID: 25090446 Free PMC article.
Chemical interrogation of the malaria kinome.
Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J. Derbyshire ER, et al. Among authors: gray ns. Chembiochem. 2014 Sep 5;15(13):1920-30. doi: 10.1002/cbic.201400025. Epub 2014 Aug 8. Chembiochem. 2014. PMID: 25111632 Free PMC article.
SnapShot: Kinase Inhibitors I.
Wang J, Gray NS. Wang J, et al. Among authors: gray ns. Mol Cell. 2015 May 21;58(4):708.e1. doi: 10.1016/j.molcel.2015.05.001. Mol Cell. 2015. PMID: 26000854 Free article.
560 results