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Sepsis alters the transcriptional and translational landscape of human and murine platelets.
Middleton EA, Rowley JW, Campbell RA, Grissom CK, Brown SM, Beesley SJ, Schwertz H, Kosaka Y, Manne BK, Krauel K, Tolley ND, Eustes AS, Guo L, Paine R 3rd, Harris ES, Zimmerman GA, Weyrich AS, Rondina MT. Middleton EA, et al. Among authors: krauel k. Blood. 2019 Sep 19;134(12):911-923. doi: 10.1182/blood.2019000067. Epub 2019 Jul 31. Blood. 2019. PMID: 31366617 Free PMC article.
Heparanase expression and activity are increased in platelets during clinical sepsis.
Eustes AS, Campbell RA, Middleton EA, Tolley ND, Manne BK, Montenont E, Rowley JW, Krauel K, Blair A, Guo L, Kosaka Y, Medeiros-de-Moraes IM, Lacerda M, Hottz ED, Neto HCF, Zimmerman GA, Weyrich AS, Petrey A, Rondina MT. Eustes AS, et al. Among authors: krauel k. J Thromb Haemost. 2021 May;19(5):1319-1330. doi: 10.1111/jth.15266. Epub 2021 Mar 11. J Thromb Haemost. 2021. PMID: 33587773 Free PMC article.
Platelet MHC class I mediates CD8+ T-cell suppression during sepsis.
Guo L, Shen S, Rowley JW, Tolley ND, Jia W, Manne BK, McComas KN, Bolingbroke B, Kosaka Y, Krauel K, Denorme F, Jacob SP, Eustes AS, Campbell RA, Middleton EA, He X, Brown SM, Morrell CN, Weyrich AS, Rondina MT. Guo L, et al. Among authors: krauel k. Blood. 2021 Aug 5;138(5):401-416. doi: 10.1182/blood.2020008958. Blood. 2021. PMID: 33895821 Free PMC article.
Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms.
Morrell CN, Mix D, Aggarwal A, Bhandari R, Godwin M, Owens P 3rd, Lyden SP, Doyle A, Krauel K, Rondina MT, Mohan A, Lowenstein CJ, Shim S, Stauffer S, Josyula VP, Ture SK, Yule DI, Wagner LE 3rd, Ashton JM, Elbadawi A, Cameron SJ. Morrell CN, et al. Among authors: krauel k. J Clin Invest. 2022 May 2;132(9):e152373. doi: 10.1172/JCI152373. J Clin Invest. 2022. PMID: 35324479 Free PMC article.
Further insights into the anti-PF4/heparin IgM immune response.
Krauel K, Schulze A, Jouni R, Hackbarth C, Hietkamp B, Selleng S, Koster A, Jensch I, van der Linde J, Schwertz H, Bakchoul T, Hundt M, Greinacher A. Krauel K, et al. Thromb Haemost. 2016 Apr;115(4):752-61. doi: 10.1160/TH15-08-0654. Epub 2015 Oct 15. Thromb Haemost. 2016. PMID: 26467272
95 results