Grollman AP - Search Results

1

Bioactivation mechanisms of N-hydroxyaristolactams: Nitroreduction metabolites of aristolochic acids.

Okuno Y, Bonala R, Attaluri S, Johnson F, Grollman AP, Sidorenko VS, Oda Y. Okuno Y, et al. Among authors: grollman ap. Environ Mol Mutagen. 2019 Dec;60(9):792-806. doi: 10.1002/em.22321. Epub 2019 Aug 16. Environ Mol Mutagen. 2019. PMID: 31374128 Free PMC article.

2

Bioactivation of the human carcinogen aristolochic acid.

Sidorenko VS, Attaluri S, Zaitseva I, Iden CR, Dickman KG, Johnson F, Grollman AP. Sidorenko VS, et al. Among authors: grollman ap. Carcinogenesis. 2014 Aug;35(8):1814-22. doi: 10.1093/carcin/bgu095. Epub 2014 Apr 17. Carcinogenesis. 2014. PMID: 24743514 Free PMC article.

3

Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells.

Hashimoto K, Zaitseva IN, Bonala R, Attaluri S, Ozga K, Iden CR, Johnson F, Moriya M, Grollman AP, Sidorenko VS. Hashimoto K, et al. Among authors: grollman ap. Carcinogenesis. 2016 Jul;37(7):647-655. doi: 10.1093/carcin/bgw045. Epub 2016 Apr 18. Carcinogenesis. 2016. PMID: 27207664 Free PMC article.

4

Quantitative determination of aristolochic acid-derived DNA adducts in rats using 32P-postlabeling/polyacrylamide gel electrophoresis analysis.

Dong H, Suzuki N, Torres MC, Bonala RR, Johnson F, Grollman AP, Shibutani S. Dong H, et al. Among authors: grollman ap. Drug Metab Dispos. 2006 Jul;34(7):1122-7. doi: 10.1124/dmd.105.008706. Epub 2006 Apr 12. Drug Metab Dispos. 2006. PMID: 16611860

5

DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells.

Attaluri S, Bonala RR, Yang IY, Lukin MA, Wen Y, Grollman AP, Moriya M, Iden CR, Johnson F. Attaluri S, et al. Among authors: grollman ap. Nucleic Acids Res. 2010 Jan;38(1):339-52. doi: 10.1093/nar/gkp815. Epub 2009 Oct 23. Nucleic Acids Res. 2010. PMID: 19854934 Free PMC article.

6

Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents.

Shibutani S, Bonala RR, Rosenquist T, Rieger R, Suzuki N, Johnson F, Miller F, Grollman AP. Shibutani S, et al. Among authors: grollman ap. Int J Cancer. 2010 Sep 1;127(5):1021-7. doi: 10.1002/ijc.25141. Int J Cancer. 2010. PMID: 20039324 Free PMC article.

7

Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts.

Sidorenko VS, Yeo JE, Bonala RR, Johnson F, Schärer OD, Grollman AP. Sidorenko VS, et al. Among authors: grollman ap. Nucleic Acids Res. 2012 Mar;40(6):2494-505. doi: 10.1093/nar/gkr1095. Epub 2011 Nov 25. Nucleic Acids Res. 2012. PMID: 22121226 Free PMC article.

8

Y-family DNA polymerase-independent gap-filling translesion synthesis across aristolochic acid-derived adenine adducts in mouse cells.

Hashimoto K, Bonala R, Johnson F, Grollman AP, Moriya M. Hashimoto K, et al. Among authors: grollman ap. DNA Repair (Amst). 2016 Oct;46:55-60. doi: 10.1016/j.dnarep.2016.07.003. Epub 2016 Jul 29. DNA Repair (Amst). 2016. PMID: 27497692 Free PMC article.

9

Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.

Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL. Chang SY, et al. Among authors: grollman ap. JCI Insight. 2017 Nov 16;2(22):e95978. doi: 10.1172/jci.insight.95978. eCollection 2017 Nov 16. JCI Insight. 2017. PMID: 29202460 Free PMC article.

10

Glutamate dehydrogenase requirement for apoptosis induced by aristolochic acid in renal tubular epithelial cells.

Romanov V, Whyard T, Bonala R, Johnson F, Grollman A. Romanov V, et al. Apoptosis. 2011 Dec;16(12):1217-28. doi: 10.1007/s10495-011-0646-5. Apoptosis. 2011. PMID: 21901531

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