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34 results

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Page 1
Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia.
Gutierrez A, Pan L, Groen RW, Baleydier F, Kentsis A, Marineau J, Grebliunaite R, Kozakewich E, Reed C, Pflumio F, Poglio S, Uzan B, Clemons P, VerPlank L, An F, Burbank J, Norton S, Tolliday N, Steen H, Weng AP, Yuan H, Bradner JE, Mitsiades C, Look AT, Aster JC. Gutierrez A, et al. Among authors: uzan b. J Clin Invest. 2014 Feb;124(2):644-55. doi: 10.1172/JCI65093. Epub 2014 Jan 9. J Clin Invest. 2014. PMID: 24401270 Free PMC article.
SPRED1, a RAS MAPK pathway inhibitor that causes Legius syndrome, is a tumour suppressor downregulated in paediatric acute myeloblastic leukaemia.
Pasmant E, Gilbert-Dussardier B, Petit A, de Laval B, Luscan A, Gruber A, Lapillonne H, Deswarte C, Goussard P, Laurendeau I, Uzan B, Pflumio F, Brizard F, Vabres P, Naguibvena I, Fasola S, Millot F, Porteu F, Vidaud D, Landman-Parker J, Ballerini P. Pasmant E, et al. Among authors: uzan b. Oncogene. 2015 Jan 29;34(5):631-8. doi: 10.1038/onc.2013.587. Epub 2014 Jan 27. Oncogene. 2015. PMID: 24469042
Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression.
Uzan B, Poglio S, Gerby B, Wu CL, Gross J, Armstrong F, Calvo J, Cahu X, Deswarte C, Dumont F, Passaro D, Besnard-Guérin C, Leblanc T, Baruchel A, Landman-Parker J, Ballerini P, Baud V, Ghysdael J, Baleydier F, Porteu F, Pflumio F. Uzan B, et al. EMBO Mol Med. 2014 Jun;6(6):821-34. doi: 10.1002/emmm.201303286. Epub 2014 Apr 6. EMBO Mol Med. 2014. PMID: 24778454 Free PMC article.
A systems biology approach for defining the molecular framework of the hematopoietic stem cell niche.
Charbord P, Pouget C, Binder H, Dumont F, Stik G, Levy P, Allain F, Marchal C, Richter J, Uzan B, Pflumio F, Letourneur F, Wirth H, Dzierzak E, Traver D, Jaffredo T, Durand C. Charbord P, et al. Among authors: uzan b. Cell Stem Cell. 2014 Sep 4;15(3):376-391. doi: 10.1016/j.stem.2014.06.005. Epub 2014 Jul 17. Cell Stem Cell. 2014. PMID: 25042701 Free article.
Rapid childhood T-ALL growth in xenograft models correlates with mature phenotype and NF-κB pathway activation but not with poor prognosis.
Poglio S, Cahu X, Uzan B, Besnard-Guérin C, Lapillonne H, Leblanc T, Baruchel A, Landman-Parker J, Petit A, Baleydier F, Amsellem S, Baud V, Ballerini P, Pflumio F. Poglio S, et al. Among authors: uzan b. Leukemia. 2015 Apr;29(4):977-80. doi: 10.1038/leu.2014.317. Epub 2014 Nov 5. Leukemia. 2015. PMID: 25371179 No abstract available.
Homeobox protein TLX3 activates miR-125b expression to promote T-cell acute lymphoblastic leukemia.
Renou L, Boelle PY, Deswarte C, Spicuglia S, Benyoucef A, Calvo J, Uzan B, Belhocine M, Cieslak A, Landman-Parker J, Baruchel A, Asnafi V, Pflumio F, Ballerini P, Naguibneva I. Renou L, et al. Among authors: uzan b. Blood Adv. 2017 May 4;1(12):733-747. doi: 10.1182/bloodadvances.2017005538. eCollection 2017 May 9. Blood Adv. 2017. PMID: 29296717 Free PMC article.
Bone marrow sites differently imprint dormancy and chemoresistance to T-cell acute lymphoblastic leukemia.
Cahu X, Calvo J, Poglio S, Prade N, Colsch B, Arcangeli ML, Leblanc T, Petit A, Baleydier F, Baruchel A, Landman-Parker J, Junot C, Larghero J, Ballerini P, Delabesse E, Uzan B, Pflumio F. Cahu X, et al. Among authors: uzan b. Blood Adv. 2017 Sep 8;1(20):1760-1772. doi: 10.1182/bloodadvances.2017004960. eCollection 2017 Sep 12. Blood Adv. 2017. PMID: 29296822 Free PMC article.
Fratricide-resistant CD1a-specific CAR T cells for the treatment of cortical T-cell acute lymphoblastic leukemia.
Sánchez-Martínez D, Baroni ML, Gutierrez-Agüera F, Roca-Ho H, Blanch-Lombarte O, González-García S, Torrebadell M, Junca J, Ramírez-Orellana M, Velasco-Hernández T, Bueno C, Fuster JL, Prado JG, Calvo J, Uzan B, Cools J, Camos M, Pflumio F, Toribio ML, Menéndez P. Sánchez-Martínez D, et al. Among authors: uzan b. Blood. 2019 May 23;133(21):2291-2304. doi: 10.1182/blood-2018-10-882944. Epub 2019 Feb 22. Blood. 2019. PMID: 30796021 Free PMC article.
34 results