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Page 1
CYP2D6 Polymorphisms and the Safety and Gametocytocidal Activity of Single-Dose Primaquine for Plasmodium falciparum.
Pett H, Bradley J, Okebe J, Dicko A, Tiono AB, Gonçalves BP, Stone W, Chen I, Lanke K, Neuvonen M, Mustaniemi AL, Eziefula AC, Gosling R, D'Alessandro U, Drakeley C, Niemi M, Bousema T. Pett H, et al. Among authors: eziefula ac. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e00538-19. doi: 10.1128/AAC.00538-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31383656 Free PMC article. Clinical Trial.
Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial.
Eziefula AC, Bousema T, Yeung S, Kamya M, Owaraganise A, Gabagaya G, Bradley J, Grignard L, Lanke KH, Wanzira H, Mpimbaza A, Nsobya S, White NJ, Webb EL, Staedke SG, Drakeley C. Eziefula AC, et al. Lancet Infect Dis. 2014 Feb;14(2):130-9. doi: 10.1016/S1473-3099(13)70268-8. Epub 2013 Nov 13. Lancet Infect Dis. 2014. PMID: 24239324 Free article. Clinical Trial.
Low-dose primaquine for falciparum malaria.
Bousema T, Eziefula AC, Pett H, Drakeley C. Bousema T, et al. Among authors: eziefula ac. Lancet Infect Dis. 2014 Aug;14(8):677. doi: 10.1016/S1473-3099(14)70842-4. Lancet Infect Dis. 2014. PMID: 25056018 Free article. No abstract available.
The gametocytocidal efficacy of primaquine in malaria asymptomatic carriers treated with dihydroartemisinin-piperaquine in The Gambia (PRINOGAM): study protocol for a randomised controlled trial.
Okebe J, Bousema T, Affara M, DiTanna G, Eziefula AC, Jawara M, Nwakanma D, Amambua-Ngwa A, Van Geertruyden JP, Drakeley C, D'Alessandro U. Okebe J, et al. Among authors: eziefula ac. Trials. 2015 Mar 1;16:70. doi: 10.1186/s13063-015-0597-1. Trials. 2015. PMID: 25887344 Free PMC article. Clinical Trial.
Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemether-lumefantrine in children with asymptomatic infection: a randomised, double-blind, placebo-controlled trial.
Gonçalves BP, Tiono AB, Ouédraogo A, Guelbéogo WM, Bradley J, Nebie I, Siaka D, Lanke K, Eziefula AC, Diarra A, Pett H, Bougouma EC, Sirima SB, Drakeley C, Bousema T. Gonçalves BP, et al. Among authors: eziefula ac. BMC Med. 2016 Mar 8;14:40. doi: 10.1186/s12916-016-0581-y. BMC Med. 2016. PMID: 26952094 Free PMC article. Clinical Trial.
Efficacy of Single-Dose Primaquine With Artemisinin Combination Therapy on Plasmodium falciparum Gametocytes and Transmission: An Individual Patient Meta-Analysis.
Stepniewska K, Humphreys GS, Gonçalves BP, Craig E, Gosling R, Guerin PJ, Price RN, Barnes KI, Raman J, Smit MR, D'Alessandro U, Stone WJR, Bjorkman A, Samuels AM, Arroyo-Arroyo MI, Bastiaens GJH, Brown JM, Dicko A, El-Sayed BB, Elzaki SG, Eziefula AC, Kariuki S, Kwambai TK, Maestre AE, Martensson A, Mosha D, Mwaiswelo RO, Ngasala BE, Okebe J, Roh ME, Sawa P, Tiono AB, Chen I, Drakeley CJ, Bousema T. Stepniewska K, et al. Among authors: eziefula ac. J Infect Dis. 2022 Apr 1;225(7):1215-1226. doi: 10.1093/infdis/jiaa498. J Infect Dis. 2022. PMID: 32778875 Free PMC article.
G6PD Polymorphisms and Hemolysis After Antimalarial Treatment With Low Single-Dose Primaquine: A Pooled Analysis of Six African Clinical Trials.
Sepúlveda N, Grignard L, Curry J, Mahey L, Bastiaens GJH, Tiono AB, Okebe J, Coulibaly SA, Gonçalves BP, Affara M, Ouédraogo A, Bougouma EC, Sanou GS, Nébié I, Lanke K, Sirima SB, Dicko A, d'Alessandro U, Clark TG, Campino S, Chen I, Eziefula AC, Gosling R, Bousema T, Drakeley C. Sepúlveda N, et al. Among authors: eziefula ac. Front Genet. 2021 Apr 9;12:645688. doi: 10.3389/fgene.2021.645688. eCollection 2021. Front Genet. 2021. PMID: 33897764 Free PMC article.
Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data.
Stepniewska K, Allen EN, Humphreys GS, Poirot E, Craig E, Kennon K, Yilma D, Bousema T, Guerin PJ, White NJ, Price RN, Raman J, Martensson A, Mwaiswelo RO, Bancone G, Bastiaens GJH, Bjorkman A, Brown JM, D'Alessandro U, Dicko AA, El-Sayed B, Elzaki SE, Eziefula AC, Gonçalves BP, Hamid MMA, Kaneko A, Kariuki S, Khan W, Kwambai TK, Ley B, Ngasala BE, Nosten F, Okebe J, Samuels AM, Smit MR, Stone WJR, Sutanto I, Ter Kuile F, Tine RC, Tiono AB, Drakeley CJ, Gosling R, Stergachis A, Barnes KI, Chen I. Stepniewska K, et al. Among authors: eziefula ac. BMC Med. 2022 Sep 16;20(1):350. doi: 10.1186/s12916-022-02504-z. BMC Med. 2022. PMID: 36109733 Free PMC article.
25 results