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Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells.
Dettmer U, Ramalingam N, von Saucken VE, Kim TE, Newman AJ, Terry-Kantor E, Nuber S, Ericsson M, Fanning S, Bartels T, Lindquist S, Levy OA, Selkoe D. Dettmer U, et al. Among authors: ericsson m. Hum Mol Genet. 2017 Sep 15;26(18):3466-3481. doi: 10.1093/hmg/ddx227. Hum Mol Genet. 2017. PMID: 28911198 Free PMC article.
Author Correction: Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes.
Nuber S, Zhang X, McCaffery TD, Moors TE, Adom MA, Hahn WN, Martin D, Ericsson M, Tripathi A, Dettmer U, Svenningsson P, Selkoe DJ. Nuber S, et al. Among authors: ericsson m. NPJ Parkinsons Dis. 2024 Mar 12;10(1):57. doi: 10.1038/s41531-024-00675-5. NPJ Parkinsons Dis. 2024. PMID: 38472218 Free PMC article. No abstract available.
The schizophrenia risk gene product miR-137 alters presynaptic plasticity.
Siegert S, Seo J, Kwon EJ, Rudenko A, Cho S, Wang W, Flood Z, Martorell AJ, Ericsson M, Mungenast AE, Tsai LH. Siegert S, et al. Among authors: ericsson m. Nat Neurosci. 2015 Jul;18(7):1008-16. doi: 10.1038/nn.4023. Epub 2015 May 25. Nat Neurosci. 2015. PMID: 26005852 Free PMC article.
315 results