Use of the dTAG system in vivo to degrade CDK2 and CDK5 in adult mice and explore potential safety liabilities.
Yenerall P, Sung T, Palyada K, Qian J, Arat S, Kumpf SW, Wang SW, Biddle K, Esparza C, Chang S, Scott W, Collette W, Winrow TS, Affolter T, Shirai N, Thibault S, Wang J, Liu L, Bauchmann M, Frey J, Steyn S, Sacaan A, Vitsky A, Ahn Y, Paul T, Lum L, Oyer J, Yang A, Hu W.
Yenerall P, et al. Among authors: palyada k.
Toxicol Sci. 2023 Jun 28;194(1):53-69. doi: 10.1093/toxsci/kfad049.
Toxicol Sci. 2023.
PMID: 37228089
Free PMC article.