Nair SK - Search Results

1

Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.

Bothwell IR, Cogan DP, Kim T, Reinhardt CJ, van der Donk WA, Nair SK. Bothwell IR, et al. Among authors: nair sk. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17245-17250. doi: 10.1073/pnas.1905240116. Epub 2019 Aug 13. Proc Natl Acad Sci U S A. 2019. PMID: 31409709 Free PMC article.

2

Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis.

Li B, Yu JP, Brunzelle JS, Moll GN, van der Donk WA, Nair SK. Li B, et al. Among authors: nair sk. Science. 2006 Mar 10;311(5766):1464-7. doi: 10.1126/science.1121422. Science. 2006. PMID: 16527981

3

In vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesis.

Choi YS, Zhang H, Brunzelle JS, Nair SK, Zhao H. Choi YS, et al. Among authors: nair sk. Proc Natl Acad Sci U S A. 2008 May 13;105(19):6858-63. doi: 10.1073/pnas.0712073105. Epub 2008 May 5. Proc Natl Acad Sci U S A. 2008. PMID: 18458342 Free PMC article.

4

An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis.

Cicchillo RM, Zhang H, Blodgett JA, Whitteck JT, Li G, Nair SK, van der Donk WA, Metcalf WW. Cicchillo RM, et al. Among authors: nair sk. Nature. 2009 Jun 11;459(7248):871-4. doi: 10.1038/nature07972. Nature. 2009. PMID: 19516340 Free PMC article.

5

Structure and mechanism of enzymes involved in biosynthesis and breakdown of the phosphonates fosfomycin, dehydrophos, and phosphinothricin.

Nair SK, van der Donk WA. Nair SK, et al. Arch Biochem Biophys. 2011 Jan 1;505(1):13-21. doi: 10.1016/j.abb.2010.09.012. Epub 2010 Sep 18. Arch Biochem Biophys. 2011. PMID: 20854789 Free PMC article. Review.

6

Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis.

Lee JH, Bae B, Kuemin M, Circello BT, Metcalf WW, Nair SK, van der Donk WA. Lee JH, et al. Among authors: nair sk. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17557-62. doi: 10.1073/pnas.1006848107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876132 Free PMC article.

7

Mechanism and substrate recognition of 2-hydroxyethylphosphonate dioxygenase.

Peck SC, Cooke HA, Cicchillo RM, Malova P, Hammerschmidt F, Nair SK, van der Donk WA. Peck SC, et al. Among authors: nair sk. Biochemistry. 2011 Aug 2;50(30):6598-605. doi: 10.1021/bi200804r. Epub 2011 Jul 8. Biochemistry. 2011. PMID: 21711001 Free PMC article.

8

Structural and mechanistic insights into C-P bond hydrolysis by phosphonoacetate hydrolase.

Agarwal V, Borisova SA, Metcalf WW, van der Donk WA, Nair SK. Agarwal V, et al. Among authors: nair sk. Chem Biol. 2011 Oct 28;18(10):1230-40. doi: 10.1016/j.chembiol.2011.07.019. Chem Biol. 2011. PMID: 22035792 Free PMC article.

9

Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7.

Agarwal V, Tikhonov A, Metlitskaya A, Severinov K, Nair SK. Agarwal V, et al. Among authors: nair sk. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4425-30. doi: 10.1073/pnas.1114224109. Epub 2012 Mar 2. Proc Natl Acad Sci U S A. 2012. PMID: 22388748 Free PMC article.

10

Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.

Lukk T, Sakai A, Kalyanaraman C, Brown SD, Imker HJ, Song L, Fedorov AA, Fedorov EV, Toro R, Hillerich B, Seidel R, Patskovsky Y, Vetting MW, Nair SK, Babbitt PC, Almo SC, Gerlt JA, Jacobson MP. Lukk T, et al. Among authors: nair sk. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4122-7. doi: 10.1073/pnas.1112081109. Epub 2012 Mar 5. Proc Natl Acad Sci U S A. 2012. PMID: 22392983 Free PMC article.

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