Eyers PA - Search Results

1

Emerging concepts in pseudoenzyme classification, evolution, and signaling.

Ribeiro AJM, Das S, Dawson N, Zaru R, Orchard S, Thornton JM, Orengo C, Zeqiraj E, Murphy JM, Eyers PA. Ribeiro AJM, et al. Among authors: eyers pa. Sci Signal. 2019 Aug 13;12(594):eaat9797. doi: 10.1126/scisignal.aat9797. Sci Signal. 2019. PMID: 31409758 Review.

2

Dawn of the dead: protein pseudokinases signal new adventures in cell biology.

Eyers PA, Murphy JM. Eyers PA, et al. Biochem Soc Trans. 2013 Aug;41(4):969-74. doi: 10.1042/BST20130115. Biochem Soc Trans. 2013. PMID: 23863165 Review.

3

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.

Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. Murphy JM, et al. Among authors: eyers pa. Biochem J. 2014 Jan 15;457(2):323-34. doi: 10.1042/BJ20131174. Biochem J. 2014. PMID: 24107129 Free PMC article.

4

The evolving world of pseudoenzymes: proteins, prejudice and zombies.

Eyers PA, Murphy JM. Eyers PA, et al. BMC Biol. 2016 Nov 11;14(1):98. doi: 10.1186/s12915-016-0322-x. BMC Biol. 2016. PMID: 27835992 Free PMC article.

5

Bio-Zombie: the rise of pseudoenzymes in biology.

Murphy JM, Farhan H, Eyers PA. Murphy JM, et al. Among authors: eyers pa. Biochem Soc Trans. 2017 Apr 15;45(2):537-544. doi: 10.1042/BST20160400. Biochem Soc Trans. 2017. PMID: 28408493 Review.

6

Live and let die: insights into pseudoenzyme mechanisms from structure.

Murphy JM, Mace PD, Eyers PA. Murphy JM, et al. Among authors: eyers pa. Curr Opin Struct Biol. 2017 Dec;47:95-104. doi: 10.1016/j.sbi.2017.07.004. Epub 2017 Aug 5. Curr Opin Struct Biol. 2017. PMID: 28787627 Review.

7

Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells.

Foulkes DM, Byrne DP, Yeung W, Shrestha S, Bailey FP, Ferries S, Eyers CE, Keeshan K, Wells C, Drewry DH, Zuercher WJ, Kannan N, Eyers PA. Foulkes DM, et al. Among authors: eyers pa, eyers ce. Sci Signal. 2018 Sep 25;11(549):eaat7951. doi: 10.1126/scisignal.aat7951. Sci Signal. 2018. PMID: 30254057 Free PMC article.

8

Tracing the origin and evolution of pseudokinases across the tree of life.

Kwon A, Scott S, Taujale R, Yeung W, Kochut KJ, Eyers PA, Kannan N. Kwon A, et al. Among authors: eyers pa. Sci Signal. 2019 Apr 23;12(578):eaav3810. doi: 10.1126/scisignal.aav3810. Sci Signal. 2019. PMID: 31015289 Free PMC article.

9

Metabolic control of BRISC-SHMT2 assembly regulates immune signalling.

Walden M, Tian L, Ross RL, Sykora UM, Byrne DP, Hesketh EL, Masandi SK, Cassel J, George R, Ault JR, El Oualid F, Pawłowski K, Salvino JM, Eyers PA, Ranson NA, Del Galdo F, Greenberg RA, Zeqiraj E. Walden M, et al. Among authors: eyers pa. Nature. 2019 Jun;570(7760):194-199. doi: 10.1038/s41586-019-1232-1. Epub 2019 May 29. Nature. 2019. PMID: 31142841 Free PMC article.

10

Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity.

Byrne DP, Shrestha S, Galler M, Cao M, Daly LA, Campbell AE, Eyers CE, Veal EA, Kannan N, Eyers PA. Byrne DP, et al. Among authors: eyers pa, eyers ce. Sci Signal. 2020 Jul 7;13(639):eaax2713. doi: 10.1126/scisignal.aax2713. Sci Signal. 2020. PMID: 32636306

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