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206 results

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Replicated evidence that endophenotypic expression of schizophrenia polygenic risk is greater in healthy siblings of patients compared to controls, suggesting gene-environment interaction. The EUGEI study.
van Os J, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome Investigators (GROUP); Arango C, O'Donovan M, Rutten BPF, Guloksuz S. van Os J, et al. Among authors: luykx jj. Psychol Med. 2020 Aug;50(11):1884-1897. doi: 10.1017/S003329171900196X. Epub 2019 Aug 15. Psychol Med. 2020. PMID: 31414981
The effect of childhood maltreatment and cannabis use on adult psychotic symptoms is modified by the COMT Val¹⁵⁸Met polymorphism.
Vinkers CH, Van Gastel WA, Schubart CD, Van Eijk KR, Luykx JJ, Van Winkel R, Joëls M, Ophoff RA, Boks MP; Genetic Risk and OUtcome of Psychosis (GROUP) Investigators; Bruggeman R, Cahn W, de Haan L, Kahn RS, Meijer CJ, Myin-Germeys I, van Os J, Wiersma D. Vinkers CH, et al. Among authors: luykx jj. Schizophr Res. 2013 Oct;150(1):303-11. doi: 10.1016/j.schres.2013.07.020. Epub 2013 Aug 15. Schizophr Res. 2013. PMID: 23954148 Free article.
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.
McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium. McLaughlin RL, et al. Among authors: luykx jj. Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038/ncomms14774. Nat Commun. 2017. PMID: 28322246 Free PMC article.
Mendelian Randomization Concerns.
Lin BD, Li Y, Luykx J. Lin BD, et al. JAMA Psychiatry. 2018 Apr 1;75(4):407. doi: 10.1001/jamapsychiatry.2018.0035. JAMA Psychiatry. 2018. PMID: 29516079 No abstract available.
Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis.
Rees E, Carrera N, Morgan J, Hambridge K, Escott-Price V, Pocklington AJ, Richards AL, Pardiñas AF; GROUP Investigators; McDonald C, Donohoe G, Morris DW, Kenny E, Kelleher E, Gill M, Corvin A, Kirov G, Walters JTR, Holmans P, Owen MJ, O'Donovan MC. Rees E, et al. Biol Psychiatry. 2019 Apr 1;85(7):554-562. doi: 10.1016/j.biopsych.2018.08.022. Epub 2018 Oct 1. Biol Psychiatry. 2019. PMID: 30420267 Free PMC article.
Patterns of obsessive-compulsive symptoms and social functioning in schizophrenia; a replication study.
Swets M, van Dijk FA, Schirmbeck F, Peen J, de Haan L, Alizadeh BZ, van Amelsvoort T, Bartels-Velthuis AA, van Beveren NJ, Bruggeman R, Cahn W, Delespaul P, Luykx JJ, Myin-Germeys I, Kahn RS, Simons CJP, van Haren NE, van Os J, van Winkel R. Swets M, et al. Among authors: luykx jj. Psychiatry Res. 2019 Jan;271:421-427. doi: 10.1016/j.psychres.2018.11.071. Epub 2018 Dec 3. Psychiatry Res. 2019. PMID: 30537664
Examining the independent and joint effects of molecular genetic liability and environmental exposures in schizophrenia: results from the EUGEI study.
Guloksuz S, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran E, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşog Lu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators; Arango C, O'Donovan M, Rutten BPF, van Os J. Guloksuz S, et al. Among authors: luykx jj. World Psychiatry. 2019 Jun;18(2):173-182. doi: 10.1002/wps.20629. World Psychiatry. 2019. PMID: 31059627 Free PMC article.
206 results