Hardy RS - Search Results

1

11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy.

Fenton CG, Doig CL, Fareed S, Naylor A, Morrell AP, Addison O, Wehmeyer C, Buckley CD, Cooper MS, Lavery GG, Raza K, Hardy RS. Fenton CG, et al. Among authors: hardy rs. Arthritis Res Ther. 2019 Aug 16;21(1):188. doi: 10.1186/s13075-019-1972-1. Arthritis Res Ther. 2019. PMID: 31420008 Free PMC article.

2

Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation.

Hardy RS, Filer A, Cooper MS, Parsonage G, Raza K, Hardie DL, Rabbitt EH, Stewart PM, Buckley CD, Hewison M. Hardy RS, et al. Arthritis Res Ther. 2006;8(4):R108. doi: 10.1186/ar1993. Arthritis Res Ther. 2006. PMID: 16846535 Free PMC article.

3

Local and systemic glucocorticoid metabolism in inflammatory arthritis.

Hardy R, Rabbitt EH, Filer A, Emery P, Hewison M, Stewart PM, Gittoes NJ, Buckley CD, Raza K, Cooper MS. Hardy R, et al. Ann Rheum Dis. 2008 Sep;67(9):1204-10. doi: 10.1136/ard.2008.090662. Epub 2008 Apr 17. Ann Rheum Dis. 2008. PMID: 18420938 Free PMC article.

4

Bone loss in inflammatory disorders.

Hardy R, Cooper MS. Hardy R, et al. J Endocrinol. 2009 Jun;201(3):309-20. doi: 10.1677/JOE-08-0568. J Endocrinol. 2009. PMID: 19443863 Review.

5

Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss.

Kaur K, Hardy R, Ahasan MM, Eijken M, van Leeuwen JP, Filer A, Thomas AM, Raza K, Buckley CD, Stewart PM, Rabbitt EH, Hewison M, Cooper MS. Kaur K, et al. Ann Rheum Dis. 2010 Jun;69(6):1185-90. doi: 10.1136/ard.2009.107466. Epub 2009 Jun 22. Ann Rheum Dis. 2010. PMID: 19549618 Free PMC article.

6

Adrenal gland and bone.

Hardy R, Cooper MS. Hardy R, et al. Arch Biochem Biophys. 2010 Nov 1;503(1):137-45. doi: 10.1016/j.abb.2010.06.007. Epub 2010 Jun 11. Arch Biochem Biophys. 2010. PMID: 20542010 Review.

7

The 11beta-hydroxysteroid dehydrogenase enzymes--arbiters of the effects of glucocorticoids in synovium and bone.

Raza K, Hardy R, Cooper MS. Raza K, et al. Rheumatology (Oxford). 2010 Nov;49(11):2016-23. doi: 10.1093/rheumatology/keq212. Epub 2010 Jul 15. Rheumatology (Oxford). 2010. PMID: 20634231 Review.

8

Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells.

Ahasan MM, Hardy R, Jones C, Kaur K, Nanus D, Juarez M, Morgan SA, Hassan-Smith Z, Bénézech C, Caamaño JH, Hewison M, Lavery G, Rabbitt EH, Clark AR, Filer A, Buckley CD, Raza K, Stewart PM, Cooper MS. Ahasan MM, et al. Arthritis Rheum. 2012 Jul;64(7):2404-13. doi: 10.1002/art.34414. Arthritis Rheum. 2012. PMID: 22294469 Free PMC article.

9

Glucocorticoid-induced osteoporosis - a disorder of mesenchymal stromal cells?

Hardy R, Cooper MS. Hardy R, et al. Front Endocrinol (Lausanne). 2011 Aug 27;2:24. doi: 10.3389/fendo.2011.00024. eCollection 2011. Front Endocrinol (Lausanne). 2011. PMID: 22654798 Free PMC article.

10

Expression of 11β-hydroxysteroid dehydrogenase enzymes in human osteosarcoma: potential role in pathogenesis and as targets for treatments.

Patel P, Hardy R, Sumathi V, Bartle G, Kindblom LG, Grimer R, Bujalska I, Stewart PM, Rabbitt E, Gittoes NJ, Cooper MS. Patel P, et al. Endocr Relat Cancer. 2012 Jul 22;19(4):589-98. doi: 10.1530/ERC-12-0079. Print 2012 Aug. Endocr Relat Cancer. 2012. PMID: 22719058

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