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The CARMA3-Bcl10-MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor-Positive Breast Cancer.
Ekambaram P, Lee JL, Hubel NE, Hu D, Yerneni S, Campbell PG, Pollock N, Klei LR, Concel VJ, Delekta PC, Chinnaiyan AM, Tomlins SA, Rhodes DR, Priedigkeit N, Lee AV, Oesterreich S, McAllister-Lucas LM, Lucas PC. Ekambaram P, et al. Among authors: hubel ne. Cancer Res. 2018 Mar 1;78(5):1225-1240. doi: 10.1158/0008-5472.CAN-17-1089. Epub 2017 Dec 19. Cancer Res. 2018. PMID: 29259013 Free PMC article.
GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein.
Cheng J, Klei LR, Hubel NE, Zhang M, Schairer R, Maurer LM, Klei HB, Kang H, Concel VJ, Delekta PC, Dang EV, Mintz MA, Baens M, Cyster JG, Parameswaran N, Thome M, Lucas PC, McAllister-Lucas LM. Cheng J, et al. Among authors: hubel ne. J Clin Invest. 2020 Feb 3;130(2):1036-1051. doi: 10.1172/JCI97040. J Clin Invest. 2020. PMID: 31961340 Free PMC article.
MALT1 Is a Targetable Driver of Epithelial-to-Mesenchymal Transition in Claudin-Low, Triple-Negative Breast Cancer.
Lee JL, Ekambaram P, Carleton NM, Hu D, Klei LR, Cai Z, Myers MI, Hubel NE, Covic L, Agnihotri S, Krappmann D, Bornancin F, Lee AV, Oesterreich S, McAllister-Lucas LM, Lucas PC. Lee JL, et al. Among authors: hubel ne. Mol Cancer Res. 2022 Mar 1;20(3):373-386. doi: 10.1158/1541-7786.MCR-21-0208. Mol Cancer Res. 2022. PMID: 34753803 Free PMC article.