Jaki T - Search Results

1

TAILoR (TelmisArtan and InsuLin Resistance in Human Immunodeficiency Virus [HIV]): An Adaptive-design, Dose-ranging Phase IIb Randomized Trial of Telmisartan for the Reduction of Insulin Resistance in HIV-positive Individuals on Combination Antiretroviral Therapy.

Pushpakom S, Kolamunnage-Dona R, Taylor C, Foster T, Spowart C, García-Fiñana M, Kemp GJ, Jaki T, Khoo S, Williamson P, Pirmohamed M; TAILoR Study Group. Pushpakom S, et al. Among authors: jaki t. Clin Infect Dis. 2020 May 6;70(10):2062-2072. doi: 10.1093/cid/ciz589. Clin Infect Dis. 2020. PMID: 31425580 Free PMC article. Clinical Trial.

2

One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint.

Whitehead J, Jaki T. Whitehead J, et al. Among authors: jaki t. Stat Med. 2009 Feb 28;28(5):828-47. doi: 10.1002/sim.3508. Stat Med. 2009. PMID: 19061203

3

A novel Phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer.

Whitehead J, Thygesen H, Jaki T, Davies S, Halford S, Turner H, Cook N, Jodrell D. Whitehead J, et al. Among authors: jaki t. Stat Med. 2012 Aug 15;31(18):1931-43. doi: 10.1002/sim.5331. Epub 2012 Apr 11. Stat Med. 2012. PMID: 22495759

4

Designing exploratory cancer trials using change in tumour size as primary endpoint.

Jaki T, André V, Su TL, Whitehead J. Jaki T, et al. Stat Med. 2013 Jul 10;32(15):2544-54. doi: 10.1002/sim.5716. Epub 2012 Dec 19. Stat Med. 2013. PMID: 23280944

5

Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function.

Yeung WY, Whitehead J, Reigner B, Beyer U, Diack C, Jaki T. Yeung WY, et al. Among authors: jaki t. Pharm Stat. 2015 Nov-Dec;14(6):479-87. doi: 10.1002/pst.1706. Epub 2015 Sep 9. Pharm Stat. 2015. PMID: 26353113

6

Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of telmisartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on combination antiretroviral therapy.

Pushpakom SP, Taylor C, Kolamunnage-Dona R, Spowart C, Vora J, García-Fiñana M, Kemp GJ, Whitehead J, Jaki T, Khoo S, Williamson P, Pirmohamed M. Pushpakom SP, et al. Among authors: jaki t. BMJ Open. 2015 Oct 15;5(10):e009566. doi: 10.1136/bmjopen-2015-009566. BMJ Open. 2015. PMID: 26474943 Free PMC article. Clinical Trial.

7

A framework for prospectively defining progression rules for internal pilot studies monitoring recruitment.

Hampson LV, Williamson PR, Wilby MJ, Jaki T. Hampson LV, et al. Among authors: jaki t. Stat Methods Med Res. 2018 Dec;27(12):3612-3627. doi: 10.1177/0962280217708906. Epub 2017 Jun 7. Stat Methods Med Res. 2018. PMID: 28589752

8

A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis.

McWilliam SJ, Rosala-Hallas A, Jones AP, Shaw V, Greenhalf W, Jaki T, Smyth AR, Smyth RL, Pirmohamed M. McWilliam SJ, et al. Among authors: jaki t. Sci Rep. 2020 Feb 4;10(1):1796. doi: 10.1038/s41598-020-58790-1. Sci Rep. 2020. PMID: 32020028 Free PMC article. Clinical Trial.

9

Author Correction: A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis.

McWilliam SJ, Rosala-Hallas A, Jones AP, Shaw V, Greenhalf W, Jaki T, Smyth AR, Smyth RL, Pirmohamed M. McWilliam SJ, et al. Among authors: jaki t. Sci Rep. 2020 Mar 10;10(1):4730. doi: 10.1038/s41598-020-61783-9. Sci Rep. 2020. PMID: 32152372 Free PMC article.

10

Estimation of treatment effects following a sequential trial of multiple treatments.

Whitehead J, Desai Y, Jaki T. Whitehead J, et al. Among authors: jaki t. Stat Med. 2020 May 20;39(11):1593-1609. doi: 10.1002/sim.8497. Epub 2020 Mar 23. Stat Med. 2020. PMID: 32207166 Free PMC article.

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