Marco-Contelles J - Search Results

1

Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors.

Svobodova B, Mezeiova E, Hepnarova V, Hrabinova M, Muckova L, Kobrlova T, Jun D, Soukup O, Jimeno ML, Marco-Contelles J, Korabecny J. Svobodova B, et al. Biomolecules. 2019 Aug 19;9(8):379. doi: 10.3390/biom9080379. Biomolecules. 2019. PMID: 31430943 Free PMC article.

2

Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues.

León R, Marco-Contelles J, García AG, Villarroya M. León R, et al. Bioorg Med Chem. 2005 Feb 15;13(4):1167-75. doi: 10.1016/j.bmc.2004.11.020. Bioorg Med Chem. 2005. PMID: 15670925

3

Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease.

Marco-Contelles J, León R, de Los Ríos C, Guglietta A, Terencio J, López MG, García AG, Villarroya M. Marco-Contelles J, et al. J Med Chem. 2006 Dec 28;49(26):7607-10. doi: 10.1021/jm061047j. J Med Chem. 2006. PMID: 17181144

4

New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties.

León R, de los Ríos C, Marco-Contelles J, Huertas O, Barril X, Luque FJ, López MG, García AG, Villarroya M. León R, et al. Bioorg Med Chem. 2008 Aug 15;16(16):7759-69. doi: 10.1016/j.bmc.2008.07.005. Epub 2008 Jul 8. Bioorg Med Chem. 2008. PMID: 18640842

5

Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.

Marco-Contelles J, León R, de los Ríos C, Samadi A, Bartolini M, Andrisano V, Huertas O, Barril X, Luque FJ, Rodríguez-Franco MI, López B, López MG, García AG, Carreiras Mdo C, Villarroya M. Marco-Contelles J, et al. J Med Chem. 2009 May 14;52(9):2724-32. doi: 10.1021/jm801292b. J Med Chem. 2009. PMID: 19374444

6

Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3-carbonitriles.

Samadi A, Valderas C, de los Ríos C, Bastida A, Chioua M, González-Lafuente L, Colmena I, Gandía L, Romero A, Del Barrio L, Martín-de-Saavedra MD, López MG, Villarroya M, Marco-Contelles J. Samadi A, et al. Bioorg Med Chem. 2011 Jan 1;19(1):122-33. doi: 10.1016/j.bmc.2010.11.040. Epub 2010 Nov 26. Bioorg Med Chem. 2011. PMID: 21163662

7

Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer's disease.

Samadi A, Chioua M, Bolea I, de Los Ríos C, Iriepa I, Moraleda I, Bastida A, Esteban G, Unzeta M, Gálvez E, Marco-Contelles J. Samadi A, et al. Eur J Med Chem. 2011 Sep;46(9):4665-8. doi: 10.1016/j.ejmech.2011.05.048. Epub 2011 May 26. Eur J Med Chem. 2011. PMID: 21669479

8

Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.

Samadi A, de los Ríos C, Bolea I, Chioua M, Iriepa I, Moraleda I, Bartolini M, Andrisano V, Gálvez E, Valderas C, Unzeta M, Marco-Contelles J. Samadi A, et al. Eur J Med Chem. 2012 Jun;52:251-62. doi: 10.1016/j.ejmech.2012.03.022. Epub 2012 Mar 30. Eur J Med Chem. 2012. PMID: 22503231

9

Novel tacrine-related drugs as potential candidates for the treatment of Alzheimer's disease.

Romero A, Cacabelos R, Oset-Gasque MJ, Samadi A, Marco-Contelles J. Romero A, et al. Bioorg Med Chem Lett. 2013 Apr 1;23(7):1916-22. doi: 10.1016/j.bmcl.2013.02.017. Epub 2013 Feb 16. Bioorg Med Chem Lett. 2013. PMID: 23481643 Free article. Review.

10

Synthesis, pharmacological assessment, and molecular modeling of 6-chloro-pyridonepezils: new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease.

Samadi A, de la Fuente Revenga M, Pérez C, Iriepa I, Moraleda I, Rodríguez-Franco MI, Marco-Contelles J. Samadi A, et al. Eur J Med Chem. 2013 Sep;67:64-74. doi: 10.1016/j.ejmech.2013.06.021. Epub 2013 Jun 25. Eur J Med Chem. 2013. PMID: 23838422

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