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Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.
Mezeiova E, Korabecny J, Sepsova V, Hrabinova M, Jost P, Muckova L, Kucera T, Dolezal R, Misik J, Spilovska K, Pham NL, Pokrievkova L, Roh J, Jun D, Soukup O, Kaping D, Kuca K. Mezeiova E, et al. Molecules. 2017 Jul 28;22(8):1265. doi: 10.3390/molecules22081265. Molecules. 2017. PMID: 28788095 Free PMC article.
Profiling donepezil template into multipotent hybrids with antioxidant properties.
Mezeiova E, Spilovska K, Nepovimova E, Gorecki L, Soukup O, Dolezal R, Malinak D, Janockova J, Jun D, Kuca K, Korabecny J. Mezeiova E, et al. J Enzyme Inhib Med Chem. 2018 Dec;33(1):583-606. doi: 10.1080/14756366.2018.1443326. J Enzyme Inhib Med Chem. 2018. PMID: 29529892 Free PMC article. Review.
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease.
Hepnarova V, Korabecny J, Matouskova L, Jost P, Muckova L, Hrabinova M, Vykoukalova N, Kerhartova M, Kucera T, Dolezal R, Nepovimova E, Spilovska K, Mezeiova E, Pham NL, Jun D, Staud F, Kaping D, Kuca K, Soukup O. Hepnarova V, et al. Among authors: mezeiova e. Eur J Med Chem. 2018 Apr 25;150:292-306. doi: 10.1016/j.ejmech.2018.02.083. Epub 2018 Mar 2. Eur J Med Chem. 2018. PMID: 29533874
1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats.
Zdarova Karasova J, Sestak V, Korabecny J, Mezeiova E, Palicka V, Kuca K, Mzik M. Zdarova Karasova J, et al. Among authors: mezeiova e. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:350-358. doi: 10.1016/j.jchromb.2018.06.034. Epub 2018 Jun 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29936371 No abstract available.
32 results