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Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab.
Kurdi AT, Glavey SV, Bezman NA, Jhatakia A, Guerriero JL, Manier S, Moschetta M, Mishima Y, Roccaro A, Detappe A, Liu CJ, Sacco A, Huynh D, Tai YT, Robbins MD, Azzi J, Ghobrial IM. Kurdi AT, et al. Among authors: bezman na. Mol Cancer Ther. 2018 Jul;17(7):1454-1463. doi: 10.1158/1535-7163.MCT-17-0998. Epub 2018 Apr 13. Mol Cancer Ther. 2018. PMID: 29654064 Free PMC article.
Alterations of NK Cell Phenotype in the Disease Course of Multiple Myeloma.
Pazina T, MacFarlane AW 4th, Bernabei L, Dulaimi E, Kotcher R, Yam C, Bezman NA, Robbins MD, Ross EA, Campbell KS, Cohen AD. Pazina T, et al. Among authors: bezman na. Cancers (Basel). 2021 Jan 10;13(2):226. doi: 10.3390/cancers13020226. Cancers (Basel). 2021. PMID: 33435153 Free PMC article.
PD-1 blockade enhances elotuzumab efficacy in mouse tumor models.
Bezman NA, Jhatakia A, Kearney AY, Brender T, Maurer M, Henning K, Jenkins MR, Rogers AJ, Neeson PJ, Korman AJ, Robbins MD, Graziano RF. Bezman NA, et al. Blood Adv. 2017 May 8;1(12):753-765. doi: 10.1182/bloodadvances.2017004382. eCollection 2017 May 9. Blood Adv. 2017. PMID: 29296719 Free PMC article.
The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells.
Richardson K, Keam SP, Zhu JJ, Meyran D, D'Souza C, Macdonald S, Campbell K, Robbins M, Bezman NA, Todd K, Quach H, Ritchie DS, Harrison SJ, Prince HM, Trapani JA, Jenkins MR, Beavis PA, Darcy PK, Neeson PJ. Richardson K, et al. Among authors: bezman na. Haematologica. 2023 Jan 1;108(1):83-97. doi: 10.3324/haematol.2021.279930. Haematologica. 2023. PMID: 35770527 Free PMC article.
Myeloma natural killer cells are exhausted and have impaired regulation of activation.
D'Souza C, Keam SP, Yeang HXA, Neeson M, Richardson K, Hsu AK, Canfield R, Bezman N, Robbins M, Quach H, Ritchie DS, Harrison SJ, Trapani JA, Prince HM, Beavis PA, Darcy PK, Neeson PJ. D'Souza C, et al. Haematologica. 2021 Sep 1;106(9):2522-2526. doi: 10.3324/haematol.2020.277525. Haematologica. 2021. PMID: 34011135 Free PMC article. No abstract available.
47 results