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Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure- based drug design.
O'Brien A, Andrews SP, Baig AH, Bortolato A, Brown AJH, Brown GA, Brown SH, Christopher JA, Congreve M, Cooke RM, De Graaf C, Errey JC, Fieldhouse C, Jazayeri A, Marshall FH, Mason JS, Mobarec JC, Okrasa K, Steele KN, Southall SM, Teobald I, Watson SP, Weir M. O'Brien A, et al. Among authors: marshall fh. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126611. doi: 10.1016/j.bmcl.2019.08.015. Epub 2019 Aug 9. Bioorg Med Chem Lett. 2019. PMID: 31447084
Progress in structure based drug design for G protein-coupled receptors.
Congreve M, Langmead CJ, Mason JS, Marshall FH. Congreve M, et al. Among authors: marshall fh. J Med Chem. 2011 Jul 14;54(13):4283-311. doi: 10.1021/jm200371q. Epub 2011 Jun 15. J Med Chem. 2011. PMID: 21615150 Free PMC article. Review. No abstract available.
Biophysical mapping of the adenosine A2A receptor.
Zhukov A, Andrews SP, Errey JC, Robertson N, Tehan B, Mason JS, Marshall FH, Weir M, Congreve M. Zhukov A, et al. Among authors: marshall fh. J Med Chem. 2011 Jul 14;54(13):4312-23. doi: 10.1021/jm2003798. Epub 2011 Jun 10. J Med Chem. 2011. PMID: 21661720 Free PMC article.
The use of GPCR structures in drug design.
Congreve M, Langmead C, Marshall FH. Congreve M, et al. Among authors: marshall fh. Adv Pharmacol. 2011;62:1-36. doi: 10.1016/B978-0-12-385952-5.00011-7. Adv Pharmacol. 2011. PMID: 21907905 Review.
123 results