Rabuka D - Search Results

1

CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity.

Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH, Gray MA, Bertozzi CR, Rabuka D, Bassik MC. Tsui CK, et al. Among authors: rabuka d. Nat Chem Biol. 2019 Oct;15(10):949-958. doi: 10.1038/s41589-019-0342-2. Epub 2019 Aug 26. Nat Chem Biol. 2019. PMID: 31451760 Free PMC article.

2

A simple LC/MRM-MS-based method to quantify free linker-payload in antibody-drug conjugate preparations.

Zmolek W, Bañas S, Barfield RM, Rabuka D, Drake PM. Zmolek W, et al. Among authors: rabuka d. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 1;1032:144-148. doi: 10.1016/j.jchromb.2016.05.055. Epub 2016 Jun 1. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27311685

3

Leveraging Formylglycine-Generating Enzyme for Production of Site-Specifically Modified Bioconjugates.

Barfield RM, Rabuka D. Barfield RM, et al. Among authors: rabuka d. Methods Mol Biol. 2018;1728:3-16. doi: 10.1007/978-1-4939-7574-7_1. Methods Mol Biol. 2018. PMID: 29404988

4

Antibody-drug conjugate library prepared by scanning insertion of the aldehyde tag into IgG1 constant regions.

Huang BCB, Kim YC, Bañas S, Barfield RM, Drake PM, Rupniewski I, Haskins WE, Rabuka D. Huang BCB, et al. Among authors: rabuka d. MAbs. 2018 Nov-Dec;10(8):1182-1189. doi: 10.1080/19420862.2018.1512327. Epub 2018 Sep 25. MAbs. 2018. PMID: 30252630 Free PMC article.

5

Site-Specific Bioconjugation Using SMARTag^® Technology: A Practical and Effective Chemoenzymatic Approach to Generate Antibody-Drug Conjugates.

Liu J, Barfield RM, Rabuka D. Liu J, et al. Among authors: rabuka d. Methods Mol Biol. 2019;2033:131-147. doi: 10.1007/978-1-4939-9654-4_10. Methods Mol Biol. 2019. PMID: 31332752

6

A Novel HER2-targeted Antibody-drug Conjugate Offers the Possibility of Clinical Dosing at Trastuzumab-equivalent Exposure Levels.

Barfield RM, Kim YC, Chuprakov S, Zhang F, Bauzon M, Ogunkoya AO, Yeo D, Hickle C, Pegram MD, Rabuka D, Drake PM. Barfield RM, et al. Among authors: rabuka d. Mol Cancer Ther. 2020 Sep;19(9):1866-1874. doi: 10.1158/1535-7163.MCT-20-0190. Epub 2020 Jul 10. Mol Cancer Ther. 2020. PMID: 32651200

7

Hierarchical assembly of model cell surfaces: synthesis of mucin mimetic polymers and their display on supported bilayers.

Rabuka D, Parthasarathy R, Lee GS, Chen X, Groves JT, Bertozzi CR. Rabuka D, et al. J Am Chem Soc. 2007 May 2;129(17):5462-71. doi: 10.1021/ja067819i. Epub 2007 Apr 11. J Am Chem Soc. 2007. PMID: 17425309 Free PMC article.

8

Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates.

Albers AE, Garofalo AW, Drake PM, Kudirka R, de Hart GW, Barfield RM, Baker J, Banas S, Rabuka D. Albers AE, et al. Among authors: rabuka d. Eur J Med Chem. 2014 Dec 17;88:3-9. doi: 10.1016/j.ejmech.2014.08.062. Epub 2014 Aug 23. Eur J Med Chem. 2014. PMID: 25176286

9

CAT-02-106, a Site-Specifically Conjugated Anti-CD22 Antibody Bearing an MDR1-Resistant Maytansine Payload Yields Excellent Efficacy and Safety in Preclinical Models.

Drake PM, Carlson A, McFarland JM, Bañas S, Barfield RM, Zmolek W, Kim YC, Huang BCB, Kudirka R, Rabuka D. Drake PM, et al. Among authors: rabuka d. Mol Cancer Ther. 2018 Jan;17(1):161-168. doi: 10.1158/1535-7163.MCT-17-0776. Epub 2017 Nov 15. Mol Cancer Ther. 2018. PMID: 29142069

10

Maytansine-bearing antibody-drug conjugates induce in vitro hallmarks of immunogenic cell death selectively in antigen-positive target cells.

Bauzon M, Drake PM, Barfield RM, Cornali BM, Rupniewski I, Rabuka D. Bauzon M, et al. Among authors: rabuka d. Oncoimmunology. 2019 Jan 22;8(4):e1565859. doi: 10.1080/2162402X.2019.1565859. eCollection 2019. Oncoimmunology. 2019. PMID: 30906660 Free PMC article.

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