Jacobson KA - Search Results

1

Survey of ribose ring pucker of signaling nucleosides and nucleotides.

Salmaso V, Jacobson KA. Salmaso V, et al. Among authors: jacobson ka. Nucleosides Nucleotides Nucleic Acids. 2020;39(1-3):322-341. doi: 10.1080/15257770.2019.1658115. Epub 2019 Aug 28. Nucleosides Nucleotides Nucleic Acids. 2020. PMID: 31460850 Free PMC article.

2

Ring-Constrained (N)-methanocarba nucleosides as adenosine receptor agonists: independent 5'-uronamide and 2'-deoxy modifications.

Lee K, Ravi G, Ji XD, Marquez VE, Jacobson KA. Lee K, et al. Among authors: jacobson ka. Bioorg Med Chem Lett. 2001 May 21;11(10):1333-7. doi: 10.1016/s0960-894x(01)00213-x. Bioorg Med Chem Lett. 2001. PMID: 11392549 Free PMC article.

3

Ribose modified nucleosides and nucleotides as ligands for purine receptors.

Jacobson KA, Ravi RG, Nandanan E, Kim HS, Moro S, Kim YC, Lee K, Barak D, Marquez VE, Ji XD. Jacobson KA, et al. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):333-41. doi: 10.1081/NCN-100002305. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563046 Free PMC article. Review.

4

Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors.

Kim HS, Ravi RG, Marquez VE, Maddileti S, Wihlborg AK, Erlinge D, Malmsjö M, Boyer JL, Harden TK, Jacobson KA. Kim HS, et al. Among authors: jacobson ka. J Med Chem. 2002 Jan 3;45(1):208-18. doi: 10.1021/jm010369e. J Med Chem. 2002. PMID: 11754592 Free PMC article.

5

Purine receptors: GPCR structure and agonist design.

Jacobson KA, Kim SK, Costanzi S, Gao ZG. Jacobson KA, et al. Mol Interv. 2004 Dec;4(6):337-47. doi: 10.1124/mi.4.6.7. Mol Interv. 2004. PMID: 15616163 Free PMC article.

6

Nucleoside modification and concerted mutagenesis of the human A3 adenosine receptor to probe interactions between the 2-position of adenosine analogs and Gln167 in the second extracellular loop.

Duong HT, Gao ZG, Jacobson KA. Duong HT, et al. Among authors: jacobson ka. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):1507-17. doi: 10.1080/15257770500265778. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438031 Free PMC article.

7

Action of nucleosides and nucleotides at 7 transmembrane-spanning receptors.

Jacobson KA, Costanzi S, Kim SK, Roh E, Joshi BV, Tchilibon S, Duong HT, Gao ZG. Jacobson KA, et al. Nucleosides Nucleotides Nucleic Acids. 2006;25(12):1425-36. doi: 10.1080/15257770600919027. Nucleosides Nucleotides Nucleic Acids. 2006. PMID: 17067963 Free PMC article. Review.

8

Synthesis of ethyl (1S,2R,3S,4S,5S)-2,3-O-(isopropylidene)-4-hydroxy-bicyclo[3.1.0]hexane-carboxylate from L-ribose: a versatile chiral synthon for preparation of adenosine and P2 receptor ligands.

Joshi BV, Melman A, Mackman RL, Jacobson KA. Joshi BV, et al. Among authors: jacobson ka. Nucleosides Nucleotides Nucleic Acids. 2008 Mar;27(3):279-91. doi: 10.1080/15257770701845253. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18260011 Free PMC article.

9

New insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptors.

Jacobson KA, Costanzi S. Jacobson KA, et al. Mol Pharmacol. 2012 Sep;82(3):361-71. doi: 10.1124/mol.112.079335. Epub 2012 Jun 13. Mol Pharmacol. 2012. PMID: 22695719 Free PMC article. Review.

10

Probing GPCR structure: adenosine and P2Y nucleotide receptors.

Jacobson KA, Costanzi S, Deflorian F. Jacobson KA, et al. Methods Enzymol. 2013;520:199-217. doi: 10.1016/B978-0-12-391861-1.00009-5. Methods Enzymol. 2013. PMID: 23332701 Free PMC article.

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