Orozco SL - Search Results

1

RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity.

Orozco SL, Daniels BP, Yatim N, Messmer MN, Quarato G, Chen-Harris H, Cullen SP, Snyder AG, Ralli-Jain P, Frase S, Tait SWG, Green DR, Albert ML, Oberst A. Orozco SL, et al. Cell Rep. 2019 Aug 27;28(9):2275-2287.e5. doi: 10.1016/j.celrep.2019.07.077. Cell Rep. 2019. PMID: 31461645 Free PMC article.

2

Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity.

Snyder AG, Hubbard NW, Messmer MN, Kofman SB, Hagan CE, Orozco SL, Chiang K, Daniels BP, Baker D, Oberst A. Snyder AG, et al. Among authors: orozco sl. Sci Immunol. 2019 Jun 21;4(36):eaaw2004. doi: 10.1126/sciimmunol.aaw2004. Sci Immunol. 2019. PMID: 31227597 Free PMC article.

3

RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.

Daniels BP, Snyder AG, Olsen TM, Orozco S, Oguin TH 3rd, Tait SWG, Martinez J, Gale M Jr, Loo YM, Oberst A. Daniels BP, et al. Cell. 2017 Apr 6;169(2):301-313.e11. doi: 10.1016/j.cell.2017.03.011. Epub 2017 Mar 30. Cell. 2017. PMID: 28366204 Free PMC article.

4

RIPK3 in cell death and inflammation: the good, the bad, and the ugly.

Orozco S, Oberst A. Orozco S, et al. Immunol Rev. 2017 May;277(1):102-112. doi: 10.1111/imr.12536. Immunol Rev. 2017. PMID: 28462521 Free PMC article. Review.

5

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.

Orozco S, Yatim N, Werner MR, Tran H, Gunja SY, Tait SW, Albert ML, Green DR, Oberst A. Orozco S, et al. Cell Death Differ. 2014 Oct;21(10):1511-21. doi: 10.1038/cdd.2014.76. Epub 2014 Jun 6. Cell Death Differ. 2014. PMID: 24902904 Free PMC article.

6

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.

Yatim N, Jusforgues-Saklani H, Orozco S, Schulz O, Barreira da Silva R, Reis e Sousa C, Green DR, Oberst A, Albert ML. Yatim N, et al. Science. 2015 Oct 16;350(6258):328-34. doi: 10.1126/science.aad0395. Epub 2015 Sep 24. Science. 2015. PMID: 26405229 Free PMC article.

7

Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency.

Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, Roca A, Lopez J, Ichim G, Proïcs E, Rubio-Patiño C, Fort L, Yatim N, Woodham E, Orozco S, Taraborrelli L, Peltzer N, Lecis D, Machesky L, Walczak H, Albert ML, Milling S, Oberst A, Ricci JE, Ryan KM, Blyth K, Tait SWG. Giampazolias E, et al. Nat Cell Biol. 2017 Sep;19(9):1116-1129. doi: 10.1038/ncb3596. Epub 2017 Aug 28. Nat Cell Biol. 2017. PMID: 28846096 Free PMC article.

8

Human ZBP1 induces cell death-independent inflammatory signaling via RIPK3 and RIPK1.

Peng R, Wang CK, Wang-Kan X, Idorn M, Kjaer M, Zhou FY, Fiil BK, Timmermann F, Orozco SL, McCarthy J, Leung CS, Lu X, Bagola K, Rehwinkel J, Oberst A, Maelfait J, Paludan SR, Gyrd-Hansen M. Peng R, et al. Among authors: orozco sl. EMBO Rep. 2022 Dec 6;23(12):e55839. doi: 10.15252/embr.202255839. Epub 2022 Oct 21. EMBO Rep. 2022. PMID: 36268590 Free PMC article.

9

Signals governing monocyte differentiation during inflammation.

Orozco SL, Canny SP, Hamerman JA. Orozco SL, et al. Curr Opin Immunol. 2021 Dec;73:16-24. doi: 10.1016/j.coi.2021.07.007. Epub 2021 Aug 16. Curr Opin Immunol. 2021. PMID: 34411882 Free PMC article. Review.

10

Characterization of a model of lethal dengue virus 2 infection in C57BL/6 mice deficient in the alpha/beta interferon receptor.

Orozco S, Schmid MA, Parameswaran P, Lachica R, Henn MR, Beatty R, Harris E. Orozco S, et al. J Gen Virol. 2012 Oct;93(Pt 10):2152-2157. doi: 10.1099/vir.0.045088-0. Epub 2012 Jul 18. J Gen Virol. 2012. PMID: 22815273 Free PMC article.

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