Fabregat I - Search Results

1

Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition.

López-Luque J, Bertran E, Crosas-Molist E, Maiques O, Malfettone A, Caja L, Serrano T, Ramos E, Sanz-Moreno V, Fabregat I. López-Luque J, et al. Among authors: fabregat i. Cancer Lett. 2019 Nov 1;464:15-24. doi: 10.1016/j.canlet.2019.08.011. Epub 2019 Aug 26. Cancer Lett. 2019. PMID: 31465839 Free PMC article.

2

The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes.

Valdés F, Alvarez AM, Locascio A, Vega S, Herrera B, Fernández M, Benito M, Nieto MA, Fabregat I. Valdés F, et al. Among authors: fabregat i. Mol Cancer Res. 2002 Nov;1(1):68-78. Mol Cancer Res. 2002. PMID: 12496370

3

Autocrine production of TGF-beta confers resistance to apoptosis after an epithelial-mesenchymal transition process in hepatocytes: Role of EGF receptor ligands.

Del Castillo G, Murillo MM, Alvarez-Barrientos A, Bertran E, Fernández M, Sánchez A, Fabregat I. Del Castillo G, et al. Among authors: fabregat i. Exp Cell Res. 2006 Sep 10;312(15):2860-71. doi: 10.1016/j.yexcr.2006.05.017. Epub 2006 Jun 7. Exp Cell Res. 2006. PMID: 16828470

4

Differential intracellular signalling induced by TGF-beta in rat adult hepatocytes and hepatoma cells: implications in liver carcinogenesis.

Caja L, Ortiz C, Bertran E, Murillo MM, Miró-Obradors MJ, Palacios E, Fabregat I. Caja L, et al. Among authors: fabregat i. Cell Signal. 2007 Apr;19(4):683-94. doi: 10.1016/j.cellsig.2006.09.002. Epub 2006 Sep 16. Cell Signal. 2007. PMID: 17055226

5

Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: role of reactive oxygen species production and glutathione depletion.

Ortiz C, Caja L, Sancho P, Bertran E, Fabregat I. Ortiz C, et al. Among authors: fabregat i. Biochem Pharmacol. 2008 May 15;75(10):1935-45. doi: 10.1016/j.bcp.2008.02.015. Epub 2008 Feb 19. Biochem Pharmacol. 2008. PMID: 18371937

6

Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity.

Carmona-Cuenca I, Roncero C, Sancho P, Caja L, Fausto N, Fernández M, Fabregat I. Carmona-Cuenca I, et al. Among authors: fabregat i. J Hepatol. 2008 Dec;49(6):965-76. doi: 10.1016/j.jhep.2008.07.021. Epub 2008 Sep 19. J Hepatol. 2008. PMID: 18845355

7

The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms.

Sancho P, Bertran E, Caja L, Carmona-Cuenca I, Murillo MM, Fabregat I. Sancho P, et al. Among authors: fabregat i. Biochim Biophys Acta. 2009 Feb;1793(2):253-63. doi: 10.1016/j.bbamcr.2008.09.003. Epub 2008 Sep 24. Biochim Biophys Acta. 2009. PMID: 18848961 Free article.

8

Role of CXCR4/SDF-1 alpha in the migratory phenotype of hepatoma cells that have undergone epithelial-mesenchymal transition in response to the transforming growth factor-beta.

Bertran E, Caja L, Navarro E, Sancho P, Mainez J, Murillo MM, Vinyals A, Fabra A, Fabregat I. Bertran E, et al. Among authors: fabregat i. Cell Signal. 2009 Nov;21(11):1595-606. doi: 10.1016/j.cellsig.2009.06.006. Epub 2009 Jul 6. Cell Signal. 2009. PMID: 19586611

9

Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4.

Caja L, Sancho P, Bertran E, Iglesias-Serret D, Gil J, Fabregat I. Caja L, et al. Among authors: fabregat i. Cancer Res. 2009 Oct 1;69(19):7595-602. doi: 10.1158/0008-5472.CAN-09-1482. Epub 2009 Sep 22. Cancer Res. 2009. PMID: 19773433

10

NADPH oxidase NOX1 controls autocrine growth of liver tumor cells through up-regulation of the epidermal growth factor receptor pathway.

Sancho P, Fabregat I. Sancho P, et al. Among authors: fabregat i. J Biol Chem. 2010 Aug 6;285(32):24815-24. doi: 10.1074/jbc.M110.114280. Epub 2010 Jun 4. J Biol Chem. 2010. PMID: 20525691 Free PMC article.

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