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Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance.
Rivadeneira DB, DePeaux K, Wang Y, Kulkarni A, Tabib T, Menk AV, Sampath P, Lafyatis R, Ferris RL, Sarkar SN, Thorne SH, Delgoffe GM. Rivadeneira DB, et al. Among authors: sarkar sn. Immunity. 2019 Sep 17;51(3):548-560.e4. doi: 10.1016/j.immuni.2019.07.003. Epub 2019 Aug 27. Immunity. 2019. PMID: 31471106 Free PMC article.
ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation.
Vendetti FP, Karukonda P, Clump DA, Teo T, Lalonde R, Nugent K, Ballew M, Kiesel BF, Beumer JH, Sarkar SN, Conrads TP, O'Connor MJ, Ferris RL, Tran PT, Delgoffe GM, Bakkenist CJ. Vendetti FP, et al. Among authors: sarkar sn. J Clin Invest. 2018 Aug 31;128(9):3926-3940. doi: 10.1172/JCI96519. Epub 2018 Aug 13. J Clin Invest. 2018. PMID: 29952768 Free PMC article.
Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production.
Ghosh A, Shao L, Sampath P, Zhao B, Patel NV, Zhu J, Behl B, Parise RA, Beumer JH, O'Sullivan RJ, DeLuca NA, Thorne SH, Rathinam VAK, Li P, Sarkar SN. Ghosh A, et al. Among authors: sarkar sn. Immunity. 2019 Jan 15;50(1):51-63.e5. doi: 10.1016/j.immuni.2018.12.013. Epub 2019 Jan 8. Immunity. 2019. PMID: 30635239 Free PMC article.
IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell.
Shao L, Hou W, Scharping NE, Vendetti FP, Srivastava R, Roy CN, Menk AV, Wang Y, Chauvin JM, Karukonda P, Thorne SH, Hornung V, Zarour HM, Bakkenist CJ, Delgoffe GM, Sarkar SN. Shao L, et al. Among authors: sarkar sn. Cancer Immunol Res. 2019 Aug;7(8):1258-1266. doi: 10.1158/2326-6066.CIR-18-0711. Epub 2019 Jun 25. Cancer Immunol Res. 2019. PMID: 31239318 Free PMC article.
Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment.
Theodoraki MN, Yerneni S, Sarkar SN, Orr B, Muthuswamy R, Voyten J, Modugno F, Jiang W, Grimm M, Basse PH, Bartlett DL, Edwards RP, Kalinski P. Theodoraki MN, et al. Among authors: sarkar sn. Cancer Res. 2018 Aug 1;78(15):4292-4302. doi: 10.1158/0008-5472.CAN-17-3985. Epub 2018 May 31. Cancer Res. 2018. PMID: 29853604 Free PMC article.
188 results