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Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ. Hebert AS, et al. Among authors: denu jm. Mol Cell. 2013 Jan 10;49(1):186-99. doi: 10.1016/j.molcel.2012.10.024. Epub 2012 Nov 29. Mol Cell. 2013. PMID: 23201123 Free PMC article.
Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ. Still AJ, et al. Among authors: denu jm. J Biol Chem. 2013 Sep 6;288(36):26209-26219. doi: 10.1074/jbc.M113.483396. Epub 2013 Jul 17. J Biol Chem. 2013. PMID: 23864654 Free PMC article.
SIRT3 mediates multi-tissue coupling for metabolic fuel switching.
Dittenhafer-Reed KE, Richards AL, Fan J, Smallegan MJ, Fotuhi Siahpirani A, Kemmerer ZA, Prolla TA, Roy S, Coon JJ, Denu JM. Dittenhafer-Reed KE, et al. Among authors: denu jm. Cell Metab. 2015 Apr 7;21(4):637-46. doi: 10.1016/j.cmet.2015.03.007. Cell Metab. 2015. PMID: 25863253 Free PMC article.
Mechanisms and Dynamics of Protein Acetylation in Mitochondria.
Baeza J, Smallegan MJ, Denu JM. Baeza J, et al. Among authors: denu jm. Trends Biochem Sci. 2016 Mar;41(3):231-244. doi: 10.1016/j.tibs.2015.12.006. Epub 2016 Jan 25. Trends Biochem Sci. 2016. PMID: 26822488 Free PMC article. Review.
Caloric Restriction Engages Hepatic RNA Processing Mechanisms in Rhesus Monkeys.
Rhoads TW, Burhans MS, Chen VB, Hutchins PD, Rush MJP, Clark JP, Stark JL, McIlwain SJ, Eghbalnia HR, Pavelec DM, Ong IM, Denu JM, Markley JL, Coon JJ, Colman RJ, Anderson RM. Rhoads TW, et al. Among authors: denu jm. Cell Metab. 2018 Mar 6;27(3):677-688.e5. doi: 10.1016/j.cmet.2018.01.014. Cell Metab. 2018. PMID: 29514073 Free PMC article.
207 results