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Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring.
Mirabella F, Desiato G, Mancinelli S, Fossati G, Rasile M, Morini R, Markicevic M, Grimm C, Amegandjin C, Termanini A, Peano C, Kunderfranco P, di Cristo G, Zerbi V, Menna E, Lodato S, Matteoli M, Pozzi D. Mirabella F, et al. Among authors: desiato g. Immunity. 2021 Nov 9;54(11):2611-2631.e8. doi: 10.1016/j.immuni.2021.10.006. Immunity. 2021. PMID: 34758338 Free PMC article.
The DNA repair protein ATM as a target in autism spectrum disorder.
Pizzamiglio L, Focchi E, Cambria C, Ponzoni L, Ferrara S, Bifari F, Desiato G, Landsberger N, Murru L, Passafaro M, Sala M, Matteoli M, Menna E, Antonucci F. Pizzamiglio L, et al. Among authors: desiato g. JCI Insight. 2021 Feb 8;6(3):e133654. doi: 10.1172/jci.insight.133654. JCI Insight. 2021. PMID: 33373327 Free PMC article.
The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes.
Scaramuzza L, De Rocco G, Desiato G, Cobolli Gigli C, Chiacchiaretta M, Mirabella F, Pozzi D, De Simone M, Conforti P, Pagani M, Benfenati F, Cesca F, Bedogni F, Landsberger N. Scaramuzza L, et al. Among authors: desiato g. EMBO Mol Med. 2021 Apr 9;13(4):e12433. doi: 10.15252/emmm.202012433. Epub 2021 Mar 5. EMBO Mol Med. 2021. PMID: 33665914 Free PMC article.
Loss of interleukin 1 signaling causes impairment of microglia- mediated synapse elimination and autistic-like behaviour in mice.
Borreca A, Mantovani C, Desiato G, Corradini I, Filipello F, Elia CA, D'Autilia F, Santamaria G, Garlanda C, Morini R, Pozzi D, Matteoli M. Borreca A, et al. Among authors: desiato g. Brain Behav Immun. 2024 Mar;117:493-509. doi: 10.1016/j.bbi.2024.01.221. Epub 2024 Feb 1. Brain Behav Immun. 2024. PMID: 38307446 Free article.
13 results